CHL1 Kit ELISA

N° du produit ABIN5510734

Détail du produit CHL1 Kit ELISA

Antigène: CHL1 (Cell Adhesion Molecule with Homology To L1CAM (Close Homolog of L1) (CHL1))

Épitope: AA 26-1083

Reactivité: Souris

Méthode de détection: Colorimetric

Type de méthode: Sandwich ELISA

Application: ELISA

Fonction: Sandwich High Sensitivity ELISA kit for Quantitative Detection of Mouse CHL1/L1CAM-2

Marque: PicoKine™

Analytical Method: Quantitative

Specificité: Expression system for standard: NSO
Immunogen sequence: E26-W1083

Réactivité croisée (Details): There is no detectable cross-reactivity with other relevant proteins.

Attributs du produit:

Tissue Specificity: Expressed in the brain, in the cerebellum and in the spinal cord. Detected in the retina and the optic nerve. Expressed in neurons and glial cells in the central nervous system and by Schwann cells in the peripheral nervous system. .

Information d'application

Plaque: Pre-coated

Restrictions: For Research Use only

Stockage

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Date de péremption: 12 months

Détail du antigène

Antigène: CHL1 (Cell Adhesion Molecule with Homology To L1CAM (Close Homolog of L1) (CHL1))

Autre désignation: Chl1 (CHL1 Produits)

Synonymes: CALL Kit ELISA, L1CAM2 Kit ELISA, CHL Kit ELISA, CHL1 Kit ELISA, Nrln1 Kit ELISA, VOPT Kit ELISA, A530023M13Rik Kit ELISA, AI465420 Kit ELISA, LICAM2 Kit ELISA, Call Kit ELISA, cell adhesion molecule L1 like Kit ELISA, chordin-like 1 Kit ELISA, cell adhesion molecule L1-like Kit ELISA, CHL1 Kit ELISA, Chrdl1 Kit ELISA, Chl1 Kit ELISA

Sujet:

Protein Function: Extracellular matrix and cell adhesion protein that plays a role in nervous system development and in synaptic plasticity. Both soluble and membranous forms promote neurite outgrowth of cerebellar and hippocampal neurons and suppress neuronal cell death. Plays a role in neuronal positioning of pyramidal neurons as well as in regulation of both the number of interneurons and the efficacy of GABAergic synapses. May play a role in regulating cell migration in nerve regeneration and cortical development. Potentiates integrin-dependent cell migration towards extracellular matrix proteins. Recruits ANK3 to the plasma membrane. .

Background: Neural cell adhesion molecule L1-like protein also known as close homolog of L1 (CHL1) is a protein that in humans is encoded by the CHL1 gene. This protein is a member of the L1 gene family of neural cell adhesion molecules. By FISH, the CHL1 gene was mapped to chromosome 3p26.1. The protein however has dynamic localisation, meaning that it has not only multiple roles in the cell, but also various locations. This protein may also play a role in the growth of certain cancers.

Synonyms: Neural cell adhesion molecule L1-like protein,Cell adhesion molecule with homology to L1CAM,Chl1-like protein,Close homolog of L1,Processed neural cell adhesion molecule L1-like protein,Chl1,Call,

Full Gene Name: Neural cell adhesion molecule L1-like protein

Cellular Localisation: Cell membrane, Single-pass type I membrane protein. Soluble forms produced by cleavage/shedding also exist.

UniProt: P70232