TFF1 Kit ELISA

N° du produit ABIN5510757

Détail du produit TFF1 Kit ELISA

Antigène: TFF1 (Trefoil Factor 1 (TFF1))

Épitope: AA 22-87

Reactivité: Souris

Méthode de détection: Colorimetric

Type de méthode: Sandwich ELISA

Application: ELISA

Fonction: Sandwich High Sensitivity ELISA kit for Quantitative Detection of Mouse TFF1

Marque: PicoKine™

Analytical Method: Quantitative

Specificité: Expression system for standard: E.coli, Immunogen sequence: Q22-F87

Réactivité croisée (Details): There is no detectable cross-reactivity with other relevant proteins.

Information d'application

Plaque: Pre-coated

Restrictions: For Research Use only

Stockage

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Date de péremption: 12 months

Détail du antigène

Antigène: TFF1 (Trefoil Factor 1 (TFF1))

Autre désignation: Tff1 (TFF1 Produits)

Synonymes: BCEI Kit ELISA, D21S21 Kit ELISA, HP1.A Kit ELISA, HPS2 Kit ELISA, pNR-2 Kit ELISA, pS2 Kit ELISA, Bcei Kit ELISA, PS2 Kit ELISA, bcei Kit ELISA, d21s21 Kit ELISA, hp1.a Kit ELISA, hps2 Kit ELISA, p1 Kit ELISA, p1-a Kit ELISA, pnr-2 Kit ELISA, ps2 Kit ELISA, tff1 Kit ELISA, xP1 Kit ELISA, xp1-L Kit ELISA, xp1 Kit ELISA, TFF1 Kit ELISA, Ps2 Kit ELISA, trefoil factor 1 Kit ELISA, trefoil factor 1 S homeolog Kit ELISA, trefoil factor 1, gene 2 S homeolog Kit ELISA, TFF1 Kit ELISA, Tff1 Kit ELISA, tff1.S Kit ELISA, tff1.2.S Kit ELISA, LOC100358238 Kit ELISA

Sujet:

Protein Function: Stabilizer of the mucous gel overlying the gastrointestinal mucosa that provides a physical barrier against various noxious agents.

Background: TFF1(Trefoil factor 1), also known as pS2, is a protein that in humans is encoded by the TFF1 gene. Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. It is found that TFF1 in normal human urine inhibited the growth of calcium oxalate crystals. Urinary TFF1 showed an inhibitory potency similar to that of nephrocalcin, and inhibition was dose dependent and inhibited by TFF1 antisera, particularly by antisera directed to the TFF1 C terminus. Concentrations and relative amounts of TFF1 in the urine of patients with idiopathic calcium oxalate kidney stones were significantly less than those found in controls. This gene, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21.

Synonyms: Trefoil factor 1, Protein pS2, Tff1, Bcei, Ps2,

Full Gene Name: trefoil factor 1

Cellular Localisation: Secreted.

UniProt: Q08423

Pathways: EGFR Signaling Pathway