RANKL Kit ELISA
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- Antigène Voir toutes RANKL (TNFSF11) Kits ELISA
- RANKL (TNFSF11) (Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11))
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Reactivité
- Humain
- Méthode de détection
- Colorimetric
- Type de méthode
- Sandwich ELISA
- Gamme de detection
- 93.7 pg/mL - 6000 pg/mL
- Seuil minimal de détection
- 93.7 pg/mL
- Application
- ELISA
- Fonction
- Sandwich ELISA for Quantitative Detection of Antigen
- Type d'échantillon
- Cell Culture Supernatant, Plasma (EDTA - heparin), Saliva, Serum, Urine
- Analytical Method
- Quantitative
- Attributs du produit
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Synonyms: MGC29565, MGC93568, OCIF, OPG, Osteoclastogenesis inhibitory factor, Osteoprotegerin, TNFRSF 11B, TNFRSF11B, TR 1, TR1, TR11B_HUMAN, Tumor necrosis factor receptor superfamily member 11B
Background: Osteoprotegerin(OPG) is identical to osteoclastogenesis inhibitory factor(OCIF), a soluble member of the tumor-necrosis factor receptor family that inhibits osteoclastogenesis. OPG is considered to play an important role in the regulation of bone resorption by modifying osteoclast differentiation. Osteoprotegerin is an independent risk factor for the progression of atherosclerosis and onset of cardiovascular disease. It can act as a soluble factor in the regulation of bone mass and imply a utility for OPG in the treatment of osteoporosis associated with increased osteoclast activity. OPG system may play a critical role in the development of osteolytic bone disease in multiple myeloma and that targeting this system may have therapeutic potential. OPG also plays a role in the vascular system. The standard product used in this kit is recombinant OPG, a 55KDa glycoprotein.
Gene Name: TNFRSF11B
Production: Natural and recombinant human OPG. There is no detectable cross-reactivity with other relevant proteins.
Standard: Expression system for standard: NSO, Immunogen sequence: E22-L401
- Top Product
- Discover our top product TNFSF11 Kit ELISA
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- Indications d'application
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Application Note: Useful in Sandwich ELISA for Quantitative Detection of Antigen. Aliquot 0.1 mL per well of the 6000pg/mL, 3000pg/mL, 1500pg/mL, 750pg/mL, 419pg/mL, 187.5pg/mL, 93.7pg/m human OPG standard solutions into the precoated 96-well plate. Add 0.1 mL of the sample diluent buffer into the control well (Zero well). Add 0.1 mL of each properly diluted sample of human cell culture supernates, serum, plasma(heparin, EDTA), saliva or urine to each empty well. It is recommended that each human OPG standard solution and each sample be measured in duplicate.
Blood Product Anticoagulant: Heparin Sodium
ELISA Dilution: 93.7pg/mL-6000pg/mL
- Volume d'échantillon
- 100 μL
- Plaque
- Pre-coated
- Restrictions
- For Research Use only
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- Stock
- RT,4 °C,-20 °C
- Stockage commentaire
- Store vials at 4°C prior to opening. Centrifuge product if not completely clear after standing at room temperature. This product is stable for 6 months at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage freeze at -20°C or below for 12 months. Avoid cycles of freezing and thawing.
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- Antigène Voir toutes RANKL (TNFSF11) Kits ELISA
- RANKL (TNFSF11) (Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11))
- Autre désignation
- OPG (TNFSF11 Produits)
- Synonymes
- CD254 Kit ELISA, ODF Kit ELISA, OPGL Kit ELISA, OPTB2 Kit ELISA, RANKL Kit ELISA, TRANCE Kit ELISA, hRANKL2 Kit ELISA, sOdf Kit ELISA, TNFSF11 Kit ELISA, Ly109l Kit ELISA, OPG Kit ELISA, Trance Kit ELISA, cd254 Kit ELISA, odf Kit ELISA, opgl Kit ELISA, optb2 Kit ELISA, rankl Kit ELISA, sodf Kit ELISA, tnfsf11 Kit ELISA, trance Kit ELISA, TNF superfamily member 11 Kit ELISA, tumor necrosis factor (ligand) superfamily, member 11 Kit ELISA, TNF receptor superfamily member 11b Kit ELISA, TNF superfamily member 11 L homeolog Kit ELISA, TNFSF11 Kit ELISA, Tnfsf11 Kit ELISA, TNFRSF11B Kit ELISA, tnfsf11.L Kit ELISA
- ID gène
- 4982
- NCBI Accession
- NP_002537
- UniProt
- O00300
- Pathways
- Signalisation NF-kappaB
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