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APP Kit ELISA

APP Reactivité: Humain Colorimetric Sandwich ELISA 312 pg/mL - 20000 pg/mL Cell Culture Supernatant, Plasma (EDTA - heparin), Serum
N° du produit ABIN6719925
  • Antigène Voir toutes APP Kits ELISA
    APP (Amyloid beta (A4) Precursor Protein (APP))
    Reactivité
    • 9
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Méthode de détection
    Colorimetric
    Type de méthode
    Sandwich ELISA
    Gamme de detection
    312 pg/mL - 20000 pg/mL
    Seuil minimal de détection
    312 pg/mL
    Application
    ELISA
    Fonction
    Sandwich ELISA for Quantitative Detection of Antigen
    Type d'échantillon
    Cell Culture Supernatant, Plasma (EDTA - heparin), Serum
    Analytical Method
    Quantitative
    Attributs du produit

    Synonyms: A4 amyloid protein, A4|A4_HUMAN, AAA, ABETA, ABPP, AD 1, Alzheimer disease 1, Alzheimer disease amyloid protein, Amyloid beta A4 protein, Amyloid beta A4 protein precursor isoform b, Amyloid beta A4 protein precursor isoform c, Amyloid beta A4 protein precursor isoform a, Amyloid of aging and alzheimer disease, APP I, Beta amyloid peptide, Cerebral vascular amyloid peptide, CTFgamma, CVAP, Human mRNA for amyloid A4 precursor of Alzheimer's disease, PreA4, Protease nexin II

    Background: Amyloid precursor protein(APP) is an integral membrane protein expressed in many tissues and concentrated in the synapses of neurons. Its primary function is not known, though it has been implicated as a regulator of synapse formation, neural plasticity and iron export. APP is best known and most commonly studied as the precursor molecule whose proteolysis generates beta amyloid(Abeta), a 39- to 42-amino acid peptide whose amyloid fibrillar form is the primary component of amyloid plaques found in the brains of Alzheimer's disease patients. APP undergoes posttranslational proteolytic processing by alpha-, beta-, and gamma-secretases. Alpha-secretase generates soluble amyloid protein, while beta- and gamma-secretases generate APP components with amyloidogenic features. These 2 processing pathways are mutually exclusive.

    Gene Name: APP

    Production: Natural and recombinant human APP. There is no detectable cross-reactivity with other relevant proteins.

    Standard: Expression system for standard: NSO, Immunogen sequence: L18-L688

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    Discover our top product APP Kit ELISA
  • Indications d'application

    Application Note: Useful in Sandwich ELISA for Quantitative Detection of Antigen. Aliquot 0.1 mL per well of the 20000pg/mL, 10000pg/mL, 5000pg/mL, 2500pg/mL, 1250pg/mL, 625pg/mL, 312pg/mL human APP standard solutions into the precoated 96-well plate. Add 0.1 mL of the sample diluent buffer into the control well (Zero well). Add 0.1 mL of each properly diluted sample of human cell culture supernates, serum or plasma(heparin, EDTA) to each empty well. It is recommended that each human APP standard solution and each sample be measured in duplicate.

    Blood Product Anticoagulant: Heparin Sodium

    ELISA Dilution: 312pg/mL-20000pg/mL

    Volume d'échantillon
    100 μL
    Plaque
    Pre-coated
    Restrictions
    For Research Use only
  • Stock
    RT,4 °C,-20 °C
    Stockage commentaire
    Store vials at 4°C prior to opening. Centrifuge product if not completely clear after standing at room temperature. This product is stable for 6 months at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage freeze at -20°C or below for 12 months. Avoid cycles of freezing and thawing.
  • Antigène Voir toutes APP Kits ELISA
    APP (Amyloid beta (A4) Precursor Protein (APP))
    Autre désignation
    APP (APP Produits)
    Synonymes
    AAA Kit ELISA, ABETA Kit ELISA, ABPP Kit ELISA, AD1 Kit ELISA, APPI Kit ELISA, CTFgamma Kit ELISA, CVAP Kit ELISA, PN-II Kit ELISA, PN2 Kit ELISA, aaa Kit ELISA, abeta Kit ELISA, abpp Kit ELISA, ad1 Kit ELISA, appi Kit ELISA, ctfgamma Kit ELISA, cvap Kit ELISA, pn2 Kit ELISA, APP Kit ELISA, APP-like Kit ELISA, APPL Kit ELISA, Abeta Kit ELISA, BcDNA:GH04413 Kit ELISA, CG7727 Kit ELISA, Dmel\\CG7727 Kit ELISA, EG:65F1.5 Kit ELISA, appl Kit ELISA, Abpp Kit ELISA, Adap Kit ELISA, Ag Kit ELISA, Cvap Kit ELISA, E030013M08Rik Kit ELISA, betaApp Kit ELISA, app Kit ELISA, wu:fj34d10 Kit ELISA, wu:fk65e12 Kit ELISA, zgc:85740 Kit ELISA, amyloid beta precursor protein Kit ELISA, amyloid beta (A4) precursor protein Kit ELISA, beta amyloid protein precursor-like Kit ELISA, amyloid beta (A4) precursor protein a Kit ELISA, amyloid beta precursor protein L homeolog Kit ELISA, APP Kit ELISA, app Kit ELISA, Appl Kit ELISA, App Kit ELISA, appa Kit ELISA, app.L Kit ELISA
    ID gène
    351
    NCBI Accession
    NP_000475
    UniProt
    P05067
    Pathways
    Caspase Cascade in Apoptosis, EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, Feeding Behaviour
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