11 products by 1 suppliers: Blue Gene
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Mouse (Murine)
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Rat (Rattus)
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Cow (Bovine)
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  • Experiment Reproducibility
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CEP57 Antigen Profile

Antigen Summary

This gene encodes a cytoplasmic protein called Translokin. This protein localizes to the centrosome and has a function in microtubular stabilization. The N-terminal half of this protein is required for its centrosome localization and for its multimerization, and the C-terminal half is required for nucleating, bundling and anchoring microtubules to the centrosomes. This protein specifically interacts with fibroblast growth factor 2 (FGF2), sorting nexin 6, Ran-binding protein M and the kinesins KIF3A and KIF3B, and thus mediates the nuclear translocation and mitogenic activity of the FGF2. It also interacts with cyclin D1 and controls nucleocytoplasmic distribution of the cyclin D1 in quiescent cells. This protein is crucial for maintaining correct chromosomal number during cell division. Mutations in this gene cause mosaic variegated aneuploidy syndrome, a rare autosomal recessive disorder. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

Alternative names and synonyms associated with CEP57

  • centrosomal protein 57 (CEP57) ELISA Kit
  • centrosomal protein 57kDa-like 1 (cep57l1) ELISA Kit
  • centrosomal protein 57 (Cep57) ELISA Kit
  • 3110002L15RIK ELISA Kit
  • CEP57 ELISA Kit
  • cep57r ELISA Kit
  • xCep57 ELISA Kit
  • c6orf182 ELISA Kit
  • 3110002l15rik ELISA Kit
  • RGD1309884 ELISA Kit
  • 3110002L15Rik ELISA Kit
  • 4921510P06Rik ELISA Kit
  • 4931428M20Rik ELISA Kit
  • AI467480 ELISA Kit
  • Tsp57 ELISA Kit
  • mKIAA0092 ELISA Kit
  • MVA2 ELISA Kit
  • PIG8 ELISA Kit
  • TSP57 ELISA Kit

Protein level used designations for CEP57

translokin , centrosomal protein 57kDa , cep57-related protein , Cep57-related protein , Centrosomal protein of 57 kDa , centrosomal protein of 57 kDa-like , centrosomal protein of 57 kDa , testis-specific protein 57 , FGF2-interacting protein , proliferation-inducing protein 8

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100445490 Pongo abelii
100013109 Monodelphis domestica
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315423 Rattus norvegicus
74360 Mus musculus
9702 Homo sapiens
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