Profil protéine

This gene encodes the largest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. Dynactin is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit interacts with dynein intermediate chain by its domains directly binding to dynein and binds to microtubules via a highly conserved glycine-rich cytoskeleton-associated protein (CAP-Gly) domain in its N-terminus. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. Mutations in this gene cause distal hereditary motor neuronopathy type VIIB (HMN7B) which is also known as distal spinal and bulbar muscular atrophy (dSBMA).

Alternative names and synonyms associated with Dynactin 1 (DCTN1)

• dynactin subunit 1 (DCTN1) anticorps
• dynactin subunit 1 (Dctn1) anticorps
• dynactin 1 (Dctn1) anticorps
• Dynactin 1, p150 subunit (DCTN1-p150) anticorps
• dynactin subunit 1 L homeolog (dctn1.L) anticorps

• AL022633 anticorps
• CG9206 anticorps
• Chip150 anticorps
• DAP-150 anticorps
• DCTN1 anticorps
• Afficher tous les alias de synonymes
• DKFZp469C1813 anticorps
• Dmel\\CG9206 anticorps
• DP-150 anticorps
• Dynactin-1 anticorps
• DYNA_DROME anticorps
• FCP-D anticorps
• Glu anticorps
• glued anticorps
• P135 anticorps
• P150 anticorps
• p150/glued anticorps
• p150 anticorps
• p150[glued] anticorps
• t1 anticorps

Protein level used designations for Dynactin 1 (DCTN1) Kits ELISA

150 kDa dynein-associated polypeptide , dynactin 1 (p150, glued homolog, Drosophila) , dynactin subunit 1 , DAP-150 , DP-150 , p150-glued , dynactin 1 , dynactin subunit 1-like , dynactin 1, retrograde axonal transport , CG9206-PA , Gl-PA , dynactin , dynactin P150 , glued , p150[glued] , p150glued , dynactin 1 (p150, glued homolog)