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anti-Mouse (Murine) GOPC Anticorps:
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Human Polyclonal GOPC Primary Antibody pour ELISA, WB - ABIN250137
Neudauer, Joberty, Macara: PIST: a novel PDZ/coiled-coil domain binding partner for the rho-family GTPase TC10. dans Biochemical and biophysical research communications 2001
Human Polyclonal GOPC Primary Antibody pour IHC (p), WB - ABIN391394
Wente, Stroh, Beaudet, Richter, Kreienkamp: Interactions with PDZ domain proteins PIST/GOPC and PDZK1 regulate intracellular sorting of the somatostatin receptor subtype 5. dans The Journal of biological chemistry 2005
Show all 2 Pubmed References
Six putative caspase (Montrer CASP3 Anticorps) substrates, including five novel proteins (ABCF1 (Montrer ABCF1 Anticorps), AKAP1 (Montrer AKAP1 Anticorps), CPE (Montrer CPE Anticorps), DOPEY1 (Montrer DOPEY1 Anticorps) and GOPC1) that may be targeted specifically by the initiator caspases 8 and 10 during the early stages of apoptosis, were identified.[caspase 10 (Montrer CASP10 Anticorps)]
PIST protein, mouse plays an important role in regulating the intracellular sorting/ localization of cadherin 23 (Montrer CDH23 Anticorps).
predominantly localized at the trans-Golgi region in round spermatids; male mice in which GOPC has been disrupted are infertile with globozoospermia
Gopc-deficient spermatids fail to assemble the peri (Montrer POSTN Anticorps)-nuclear structures in round-headed spermatozoa during spermatogenesis.
The coiled tail of the round-headed spermatozoa appears during epididymal passage in Gopc-deficient mice.
Transmission electron microscope (TEM (Montrer TNMD Anticorps)) images of the spermatozoa were studied quantitatively to analyze disorganization processes during epididymal passage in Gopc knockout mice.
PIST, a Golgi-associated PDZ domain-containing protein, interacts with PCDH15 (Montrer PCDH15 Anticorps) in the plasma membrane.
CAL (Montrer FBLIM1 Anticorps) can regulate the anterograde trafficking, the internalization as well as the signaling of CRFR1 (Montrer CRHR1 Anticorps) via modulating the post-translational modifications that the receptor undergoes at the Golgi apparatus.
CAL (Montrer FBLIM1 Anticorps) overexpression retards B2AR (Montrer ADRB2 Anticorps) expression in Golgi apparatus and reduces the receptor expression in the plasma membrane.
Six out of 65 (9%) BTC patients were positive for the FIG-ROS1 fusion, comprising two out of 14 (14%) gallbladder carcinoma (GBC) patients and four out of 25 (16%) extrahepatic cholangiocarcinoma (ECC) patients.
Our data suggest that PIST contributes to the fine-tuning of b1AR (Montrer ADRB1 Anticorps) sorting both during biosynthetic and postendocytic trafficking
None of 268 gliomas analysed showed the FIG-ROS1(L) rearrangement.
Stereochemical preferences modulate affinity and selectivity among CAL (Montrer FBLIM1 Anticorps) PDZ domain protein (Montrer INADL Anticorps) variants that bind CFTR (Montrer CFTR Anticorps).
FIG-ROS (Montrer ROS1 Anticorps) fusion protein, which is found in a subset of intrahepatic cholangiocarcinoma patients, accelerates cholangiocarcinogenesis.
Data indicate that E3 ubiquitin ligase (Montrer MUL1 Anticorps) MARCH2 (Montrer MARCH2 Anticorps) co-immunoprecipitated and co-localized with CAL (Montrer FBLIM1 Anticorps) and syntaxin 6 (STX6 (Montrer STX6 Anticorps)), and show the ubiquitination of CFTR (Montrer CFTR Anticorps) by MARCH2 (Montrer MARCH2 Anticorps).
The coiled-coil domain of PIST was then purified to homogeneity and crystallized at 293 K. Finally, X-ray diffraction data were collected to a resolution of 4.0 A from a crystal belonging to the hexagonal space group P6(2)22 or P6(4)22.
This gene encodes a Golgi protein with a PDZ domain. The PDZ domain is globular and proteins which contain them bind other proteins through short motifs near the C-termini. Mice which are deficient in the orthologous protein have globozoospermia and are infertile. Multiple transcript variants encoding different isoforms have been found for this gene.
golgi-associated PDZ and coiled-coil motif containing
, golgi associated PDZ and coiled-coil motif containing
, Golgi-associated PDZ and coiled-coil motif-containing protein
, golgi-associated PDZ and coiled-coil motif-containing protein-like
, Golgi-associated PDZ and coiled-coil motif-containing protein-like
, PDZ domain-containing protein PIST
, PDZ protein interacting specifically with TC10
, PDZ/coiled-coil domain binding partner for the rho-family GTPase TC10
, CFTR-associated ligand
, Golgi associated PDZ and coiled-coil motif containing protein
, dJ94G16.2 PIST
, fused in glioblastoma