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MDS1 and EVI1 Complex Locus Produits

(MDS1 and EVI1 Complex Locus (MECOM))

Catégories

The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Mar 2011].

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Catégories MDS1 and EVI1 Complex Locus en vedette

MDS1 and EVI1 Complex Locus Anticorps

High quality antibodies with extensive validation data.

MDS1 and EVI1 Complex Locus Kits ELISA

Reliable ELISA kits for a wide range of species.

MDS1 and EVI1 Complex Locus Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

MDS1 and EVI1 Complex Locus recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application WB, IHC, IF
Validations
  • (5)
N° du produit ABIN7074575
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC (p)
Validations
  • (3)
N° du produit ABIN5583378
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application WB, IHC
Validations
  • (4)
N° du produit ABIN2777403
Quantité 100 μL
Fiche technique Fiche technique

MDS1 and EVI1 Complex Locus recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method
Validations
N° du produit ABIN1141785
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method
Validations
N° du produit ABIN1141786
Quantité 96 tests
Fiche technique Fiche technique

MDS1 and EVI1 Complex Locus recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1310610
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1310612
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1310620
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits MDS1 and EVI1 Complex Locus

Ghisi, Kats, Masson, Li, Kratina, Vidacs, Gilan, Doyle, Newbold, Bolden, Fairfax, de Graaf, Firth, Zuber, Dickins, Corcoran, Dawson, Belz, Johnstone: "Id2 and E Proteins Orchestrate the Initiation and Maintenance of MLL-Rearranged Acute Myeloid Leukemia." dans: Cancer cell, Vol. 30, Issue 1, pp. 59-74, (2016) (PubMed).

Shen, Chen, Zhang, Yin, Ning, Su, Lin, Song, Wang, Ma, Zhao, Yu, Zhang: "The PU.1-Modulated MicroRNA-22 Is a Regulator of Monocyte/Macrophage Differentiation and Acute Myeloid Leukemia." dans: PLoS genetics, Vol. 12, Issue 9, pp. e1006259, (2016) (PubMed).

Cristóbal, Garcia-Orti, Cirauqui, Cortes-Lavaud, García-Sánchez, Calasanz, Odero: "Overexpression of SET is a recurrent event associated with poor outcome and contributes to protein phosphatase 2A inhibition in acute myeloid leukemia." dans: Haematologica, Vol. 97, Issue 4, pp. 543-50, (2012) (PubMed).

Konrad, Karger, Hackl, Schwarzinger, Herbacek, Wieser: "Inducible expression of EVI1 in human myeloid cells causes phenotypes consistent with its role in myelodysplastic syndromes." dans: Journal of leukocyte biology, Vol. 86, Issue 4, pp. 813-22, (2009) (PubMed).

Synonymes et noms alternatifs relatifs à MDS1 and EVI1 Complex Locus

MDS1 and EVI1 complex locus (MECOM), MDS1 and EVI1 complex locus (Mecom), MDS1 and EVI1 complex locus (mecom), MDS1 and EVI1 complex locus L homeolog (mecom.L), MDS1 and EVI1 complex locus S homeolog (mecom.S), AML1-EVI-1, D630039M04Rik, Evi-1, evi-1, EVI1, Evi1, evi1, evi1-B, im:7140716, Jbo, Mds, MDS1, Mds1, MDS1-EVI1, Mds1-Evi1, mecom, mecom-a, mecom-b, PRDM3, Prdm3, prdm3, xEvi-1, Znfpr1b1

Protein level used designations for MDS1 and EVI1 Complex Locus

  • AML1-EVI-1 fusion protein
  • MDS1 and EVI1 complex locus protein EVI1
  • MDS1 and EVI1 complex locus protein MDS1
  • ecotropic virus integration site 1 protein homolog
  • myelodysplasia syndrome-associated protein 1
  • oncogene EVI1
  • zinc finger protein Evi1
  • ecotropic viral integration site 1
  • ecotropic virus integration site 1 protein
  • myelodysplasia syndrome 1 homolog
  • myelodysplasia syndrome 1 protein homolog
  • PR domain containing 3
  • MDS1 and EVI1 complex locus
  • MDS1 and EVI1 complex locus protein EVI1-like
  • MDS1 and EVI1 complex locus protein EVI1-A
  • ecotropic virus integration site 1 protein homolog-A
  • myelodysplasia syndrome 1-ectopic viral integration site 1
  • Ecotropic virus integration site 1 protein homolog-B
  • MDS1 and EVI1 complex locus protein EVI1-B
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