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anti-Human BHMT2 Anticorps:
anti-Mouse (Murine) BHMT2 Anticorps:
anti-Rat (Rattus) BHMT2 Anticorps:
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A three-way interaction among maternal and fetal variants in BHMT2, GSTP1 (Montrer GSTP1 Anticorps) and GPX3 (Montrer GPX3 Anticorps) contribute to congenital heart defects
The faster evolutionary rate of BHMT2 overall suggests that selective constraints were reduced relative to BHMT (Montrer BHMT Anticorps).
Multiple SNPs in BHMT (Montrer BHMT Anticorps) and BHMT2 were identified to be associated with the occurrence of infant obstructive heart defects and interaction effects with maternal use of folic acid supplements.
No significant level of association was found with cleft lip with or without cleft palate and BHMT2 variants.
gene-gene interaction analysis revealed a significant epistatic interaction of BHMT2 (rs673752), PEMT (Montrer PEMT Anticorps) (rs12325817), and PCYT1A (Montrer PCYT1A Anticorps) (rs712012) with maternal NCL (Montrer CLN5 Anticorps)/P susceptibility.
Hyperhomocysteinemia, a risk factor for coronary diseases, can be caused by genetic mutations in BHMT2 metabolism.
Betaine-homocysteine S-methyltransferase-2 is an S-methylmethionine-homocysteine methyltransferase.
Common genetic variation in BHMT (Montrer BHMT Anticorps) and BHMT2 and functionally characterized BHMT (Montrer BHMT Anticorps) SNPs.
the mouse liver extracts, containing the BHMT-2 homocysteine methyltransferase candidate for a similar activity, recognizes (S,S)-AdoMet (Montrer MAT1A Anticorps) but not (R,S)-AdoMet (Montrer MAT1A Anticorps).
Betaine-homocysteine methyltransferase 2 (Bhmt2) was identified as a diet-dependent genetic factor that affected susceptibility to acetaminophen-induced liver toxicity in mice.
Homocysteine is a sulfur-containing amino acid that plays a crucial role in methylation reactions. Transfer of the methyl group from betaine to homocysteine creates methionine, which donates the methyl group to methylate DNA, proteins, lipids, and other intracellular metabolites. The protein encoded by this gene is one of two methyl transferases that can catalyze the transfer of the methyl group from betaine to homocysteine. Anomalies in homocysteine metabolism have been implicated in disorders ranging from vascular disease to neural tube birth defects such as spina bifida. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
betaine-homocysteine methyltransferase 2
, Betaine--homocysteine S-methyltransferase 2
, betaine--homocysteine S-methyltransferase 2
, betaine--homocysteine S-methyltransferase 2-like
, S-methylmethionine--homocysteine S-methyltransferase BHMT2
, SMM-hcy methyltransferase