Aperçu des produits pour anti-Carboxylesterase 1 (CES1) Anticorps

Full name:: anti-Carboxylesterase 1 Anticorps (CES1)

Chez www.anticorps-enligne.fr sont 80 Carboxylesterase 1 (CES1) Anticorps de 22 de différents fournisseurs disponibles. De plus, nous expédions Carboxylesterase 1 Kits (17) et Carboxylesterase 1 Protéines (15) et beaucoup plus de produits pour cette protéine. Un total de 122 Carboxylesterase 1 produits sont actuellement listés.

Synonymes:: ACAT, APLE, CE-1, CEH, CES, Ces-1, CES-K1, CES1, CES2, CESDD1, hCE-1, HMSE, HMSE1, PCE-1, PMPMEase, REH, Ses-1, SES1, TGH

afficher tous les anticorps	Gène	GeneID	UniProt
	CES1	1066	P23141
	CES1	12623	Q8VCC2
	CES1
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Pathways pertinentes pour anti-Carboxylesterase 1 Anticorps

Monocarboxylic Acid Catabolic Process

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Human Carboxylesterase 1 (CES1) interaction partners

These results are consistent with a model in which abrogation of CES1 function attenuates the CYP27A1-LXRalpha-ABCA1 signaling axis by depleting endogenous ligands for the nuclear receptors PPARgamma, RAR, and/or RXR that regulate cholesterol homeostasis.
Anordrin is predominantly catalyzed by CES1 and CES2 to generate the main active metabolite, anordiol.
genetic association and pharmacogenomic studies in population in Finland: Data suggest that 2 SNPs in CES1 (rs12443580, rs8192935) are associated with variations in expression of CES1 (in whole blood samples but not in liver); these CES1 SNPs do not affect pharmacokinetics or pharmacodynamics of clopidogrel, an inhibitor of platelet aggregation. A missense mutation in CES1 (rs71647871) impairs hydrolysis of clopidogrel.
The frequencies of SNVs with a potential functional impact were below 0.02 suggesting limited pharmacogenetic potential for CES1 genotyping.
none of the selected variations of CES1 had a clinically relevant impact on the metabolism of enalapril
Study revealed that several nsSNPs significantly impaired CES1 activity on the metabolism of the CES1 substrates enalapril, clopidogrel, and sacubitril.
Suggest a primary metabolic role for CES1 in the capacity of skin/keratinocytes to mediated biotransformation of penta-ethyl ester prodrug of DTPA.
These data suggest that infants younger than 3 weeks of age would exhibit significantly lower CES1- and CES2-dependent metabolic clearance compared with older individuals.
The intestinal transport of oseltamivir, a hCE1 (Montrer RNGTT Anticorps) substrate, could be evaluated in subclone #78 cell monolayers.
An association was identified with a genetic variation in CES1 and early-onset capecitabine-related toxicity.

Mouse (Murine) Carboxylesterase 1 (CES1) interaction partners

Loss of CES1 is associated with the susceptibility to high cholesterol diet-induced liver injury.
Hepatic Ces1g/Es-x plays a critical role in limiting hepatic steatosis, very low-density lipoprotein assembly and in augmenting insulin (Montrer INS Anticorps) sensitivity.
Data indicate that organic anion-transporting polypeptides Oatp1a/1b-null mice had increased levels of carboxylesterase (Ces) enzymes, which caused higher conversion of irinotecan to SN-38 in plasma, potentially complicating pharmacokinetic analyses.
Hepatic CES1 plays a critical role in regulating both lipid and carbohydrate metabolism and FXR (Montrer NR1H4 Anticorps)-controlled lipid homeostasis

Pig (Porcine) Carboxylesterase 1 (CES1) interaction partners

Data suggest that substrate specificity of porcine liver esterase (Montrer ESD Anticorps) extends to the plasticizers di-(2-ethylhexyl) trimellitates.
One novel isoform termed alternative pig liver esterase (Montrer ESD Anticorps) (APLE) was found to hydrolyze methyl-(2R,4E)-5-chloro-2-isopropyl-4-pentenoate in a highly stereoselective manner (E>200).
The objective of this study is to explore the mechanisms that regulate TGH expression in porcine adipocyte and its role in fasting-induced (Montrer C10orf10 Anticorps) and Isoproterenol-stimulated lipolysis in porcine primary adipocytes.
PMPMEase was purified to apparent homogeneity from porcine liver supernatant.

Carboxylesterase 1 (CES1) profil antigène

Antigen Summary

This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. Mutations of this gene cause carboxylesterase 1 deficiency. Three transcript variants encoding three different isoforms have been found for this gene.

Alternative names and synonyms associated with Carboxylesterase 1 (CES1)

carboxylesterase 1 (CES1) anticorps
liver carboxylesterase 1 (CpipJ_CPIJ013026) anticorps
liver carboxylesterase 1 (CpipJ_CPIJ016339) anticorps
liver carboxylesterase (LOC100009551) anticorps
carboxylesterase 1G (Ces1g) anticorps
liver carboxylesterase 1 (LOC454097) anticorps
liver carboxylesterase 1 (LOC699486) anticorps
liver carboxylesterase 1 (CES1) anticorps
carboxylesterase 1 (monocyte/macrophage serine esterase 1) (CES1) anticorps
liver carboxylesterase 1 (LOC100050915) anticorps

ACAT anticorps
APLE anticorps
CE-1 anticorps
CEH anticorps
CES anticorps
Ces-1 anticorps
CES-K1 anticorps
CES1 anticorps
CES2 anticorps
CESDD1 anticorps
hCE-1 anticorps
HMSE anticorps
HMSE1 anticorps
PCE-1 anticorps
PMPMEase anticorps
REH anticorps
Ses-1 anticorps
SES1 anticorps
TGH anticorps

Protein level used designations for CES1

, , , , , , , , , , , , , , , , , , , , , acyl coenzyme A:cholesterol acyltransferase acyl-coenzyme A:cholesterol acyltransferase brain carboxylesterase hBr1 carboxylesterase 1 (monocyte/macrophage serine esterase 1) carboxylesterase 2 (liver) cholesteryl ester hydrolase cocaine carboxylesterase egasyn human monocyte/macrophage serine esterase 1 liver carboxylesterase 1 methylumbelliferyl-acetate deacetylase 1 monocyte/macrophage serine esterase retinyl ester hydrolase serine esterase 1 triacylglycerol hydrolase ES-x carboxylesterase 1 carboxylesterase D1 alternative pig liver esterase liver carboxylesterase prenylated methylated protein methyl esterase proline-beta-naphthylamidase

GENE ID	SPECIES
1066	Homo sapiens
6045866	Culex quinquefasciatus
6050034	Culex quinquefasciatus
100009551	Oryctolagus cuniculus
12623	Mus musculus
403643	Canis lupus familiaris
454097	Pan troglodytes
493774	Felis catus
699486	Macaca mulatta
100144615	Monodelphis domestica
397478	Sus scrofa
512098	Bos taurus
100050915	Equus caballus
102129184	Macaca fascicularis

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