Use your antibodies-online credentials, if available.
Il n’y a pas de produits dans votre liste de comparaison.
Votre panier est vide.
Afficher toutes les espèces
Afficher tous les synonymes
Sélectionnez vos espèces et l'application
anti-Human IGFBP3 Anticorps:
anti-Mouse (Murine) IGFBP3 Anticorps:
anti-Rat (Rattus) IGFBP3 Anticorps:
Vous arrivez à notre recherche pré-filtrée.
Human Polyclonal IGFBP3 Primary Antibody pour IHC (p), ELISA - ABIN3043859
Pu, Zheng, Zhang, Xiao, Xu, Liu, Wang, Wen, Zhou, Wu: Higher expression of mRNA and protein of insulin-like growth factor binding protein-3 in old rat penile tissues: implications for erectile dysfunction. dans The journal of sexual medicine 2011
Show all 2 Pubmed References
Human Polyclonal IGFBP3 Primary Antibody pour IHC (p), WB - ABIN3044421
Pu, Wen, Liu, Zheng, Xiao, Xu, Wang, Li, Zhang: shRNA constructs targeting IGFBP-3 alleviate age related erectile dysfunction in the rat. dans The Journal of urology 2014
Show all 2 Pubmed References
Human Polyclonal IGFBP3 Primary Antibody pour IF (p), IHC (p) - ABIN686497
Yuan, Han, Cong, Ge, Ma, Dai, Li, Bi: Docetaxel-loaded solid lipid nanoparticles suppress breast cancer cells growth with reduced myelosuppression toxicity. dans International journal of nanomedicine 2014
Human Polyclonal IGFBP3 Primary Antibody pour ELISA, WB - ABIN314305
Lin, Manson, Lee, Cook, Buring, Zhang: Intakes of calcium and vitamin D and breast cancer risk in women. dans Archives of internal medicine 2007
Peripheral totalIGF-1 and IGFBP-3 were associated with better performance in attention, visuospatial, and global cognitive domains, independent of the gait speed.
B-Myb (Montrer MYBL2 Anticorps) is an independent prognostic marker and serves as a potential target in the diagnosis and/or treatment of NSCLC, and that B-Myb (Montrer MYBL2 Anticorps) functions as a tumor-promoting gene by targeting IGFBP3 in NSCLC cells.
IGFBP-3 up-regulates PI3K (Montrer PIK3CA Anticorps)/Akt (Montrer AKT1 Anticorps)/mTOR (Montrer FRAP1 Anticorps) signaling pathway and down-regulates autophagy during cell aging. The decrease of IGFBP-3 expression in senescence and cell aging by H2O2 leads to up-regulation of mTOR (Montrer FRAP1 Anticorps) and p53 (Montrer TP53 Anticorps) signaling pathway, suggesting that IGFBP-3 could play a key role as an aging marker
Report deregulation of IGF1 (Montrer IGF1 Anticorps)/IGFBP3 expression in breast cancer correlating with neoplasm staging and histologic grade.
Low IGFBP-3 serum levels were associated with Pancreatic Cancer.
IGFBP-3 Interacts with the Vitamin D Receptor (Montrer VDR Anticorps) in Insulin (Montrer INS Anticorps) Signaling Associated with Obesity in Visceral Adipose Tissue
Circulating sex steroids, prolactin (Montrer PRL Anticorps), insulin (Montrer INS Anticorps)-like growth factor (IGF) I (Montrer IGF1 Anticorps), IGF-binding protein 3, and sex hormone-binding globulin (SHBG (Montrer SHBG Anticorps)) were evaluated using backward elimination separately in women pre- and postmenopausal at blood collection.
IGFBP3, a gene associated with preeclampsia pathophysiology, was validated as a target gene of miR (Montrer MLXIP Anticorps)-210
analysis of IGFBP3-IGF1 (Montrer IGF1 Anticorps) correlation with the risk of esophageal carcinoma; the free form of IGFBP3, might be inversely associated with esophageal cancer incidence
Our data indicate that targeting IGFBP-3-dependent signaling pathways through gefitinib-FTY720 co-therapy may be effective in many basal-like breast cancers, and suggest tissue IGFBP-3 and CD44 (Montrer CD44 Anticorps) measurement as potential biomarkers of treatment efficacy.
Igfbp3-null mouse model was generated in combination with Kras(G12D) to compare the tumor burden. Then, IGF-dependent signaling was assessed after expressing wild-type or a mutant IGFBP3 without IGF binding (Montrer HTRA1 Anticorps) capacity in non-small cell lung cancer (NSCLC) cells
endogenous (circulating and/or stromal) IGFBP-3 is stimulatory to adipose tissue expansion and enhances mammary tumor growth in immune-competent mice, potentially by suppressing T-cell infiltration into tumors.
High Igfbp3 expression is associated with skin squamous cell carcinoma.
The study shows that the anti-tumoral effect of IGFBP-3 is due to inhibition of the Wnt (Montrer WNT2 Anticorps) pathway and depends upon the presence of CD44 (Montrer CD44 Anticorps), a receptor protein known to modulate Wnt (Montrer WNT2 Anticorps) signaling.
IGFBP-3 influences severity of DSS (Montrer PMP22 Anticorps)-induced colitis.
our studies found that the deletion of IGFBP3 results in behavioral impairments that are associated with abnormal synaptic function and monoaminergic neurotransmission, which helps to characterize the critical role of IGFBP3 in the brain
IGFBP-3 is an aggravating factor during hepatic ischemia-repefusion injury.
An increase in IGFBP-3 post-trauma may play an important role in limiting trauma-induced inflammatory and apoptotic pathways leading to retinal damage.
Even though knockout of IGFBP-3 is associated with only a subtle phenotype under control conditions, our results reveal that loss of this gene has measurable effects on breast carcinogenesis and breast cancer metastasis.
Igfbp3 is a marker for culture-activated hepatic stellate cells and plays a role in HSC (Montrer FUT1 Anticorps) migration.
The study demonstrates that hyaluronan acts as an anti-inflammatory molecule by down-regulating IFNAR1 and IFNAR2, the signaling molecules STAT1, STAT2, JAK1 and the downstream apoptotic targets IGFBP3 and IFIT3.
These data suggest that endogenous IGFBP-3 plays a role in intrinsic apoptosis by facilitating phosphorylation and nuclear export of Nur77 (Montrer NR4A1 Anticorps) to the cytoplasm where it exerts its apoptotic effect.
The present study suggests that the insulin (Montrer INS Anticorps) like growth factor (IGF) system or imbalances between IGF and IGF binding (Montrer HTRA1 Anticorps) proteins may be involved in cystic ovary disease of cattle.
spatial and temporal patterns of expression of IGFBP-2 (Montrer IGFBP2 Anticorps) and -3 were markedly altered in the placentomes of nuclear transfer pregnancies
stimulation of IGFBP-3 mRNA levels by mitogens is regulated through both the PI3K and MAPK (Montrer MAPK1 Anticorps) pathways in bovine mammary epithelial cells
Preincubation of erythroid cells with thrombospondin 1 (Montrer THBS1 Anticorps) eliminated the inhibitory activity of IGFBP-3
GH, IGF-I (Montrer IGF1 Anticorps) and IGF-IBP3 regulated the growth and development traits in different growth period.
delivery of insulin-like growth factor-1 (IGF-1 (Montrer IGF1 Anticorps), delivered at concentrations of 0, 10, 50, and 100 ng/mL) affects the endogenous expression of IGF-1 (Montrer IGF1 Anticorps), its receptor (IGF-1R (Montrer IGF1R Anticorps)), and a well known IGF-1 (Montrer IGF1 Anticorps) binding protein (IGFBP-3) by articular chondrocytes
Multivariable adjusted analyses did not reveal a statistically significant linear relationship between IGF1 (Montrer IGF1 Anticorps) or IGFBP3 concentrations or their molar ratio and risk of myocardial infarction
Endogenous IGFBP-3 is required for both growth factor-stimulated cell proliferation and cytokine-induced apoptosis in mammary epithelial cells.
insulin-like growth factor binding protein 3 exerts its ligand-independent action by antagonizing bone morphogenetic protein 2 (Montrer BMP4 Anticorps) in zebrafish embryos
IGFBP-3 plays an important role in regulating pharyngeal cartilage and inner ear development and growth in zebrafish.
IGF-I (Montrer IGF1 Anticorps), IGF-II, and IGFBP-3 mRNA were positively correlated with IGF-IR from 50E to 180D, suggesting that the expression of IGF-system genes exhibits specific developmental patterns in the skeletal muscle tissues.
Increased oxidative stress from high glucose enhances IGFBP-3 expression, inducing apoptosis
Even though LRP-1 (Montrer LRP1 Anticorps) mRNA and protein levels were dramatically reduced in LRP-1 (Montrer LRP1 Anticorps)-silenced L6 cells compared with mock-silenced controls, rpIGFPB-3 suppressed proliferation rate to the same extent in both LRP-1 (Montrer LRP1 Anticorps)-silenced and mock-silenced cultures.
cloning and sequencing; regulation of IGFBP-3 transcription by FSH (Montrer BRD2 Anticorps) suggests a role for IGFBP-3 in follicular development that may be independent of IGF-I (Montrer IGF1 Anticorps)
Follicle-stimulating hormone stimulation of IGFBP-3 transcription is mediated by cAMP via the PKA pathway and requires the P1-3 kinase and likely the MAPK (Montrer MAPK1 Anticorps) pathways.
TAF4b may thus be the TFIID (Montrer TBP Anticorps) component that binds to the TBP (Montrer TBP Anticorps) site on the IGFBP-3 promoter and is essential for FSH (Montrer BRD2 Anticorps) induction of IGFBP-3.
The results suggest that the expression of IGF2 and IGFBP3 mRNA in the adipose tissue of pigs exhibits specific developmental changes and different patterns between the two pig breeds.
allelic frequency of TAT (Montrer C6orf134 Anticorps) in Chinese breeds was over 50%; allelic frequency of GGC (Montrer GGCT Anticorps) was over 50% in all European breeds. TAT/TAT (Montrer C6orf134 Anticorps) pigs scored higher in meat color than GGC/GGC (Montrer GGCT Anticorps) pigs. results implied that IGFBP-3 may affect meat quality & carcass traits.
Data suggest that metabolism of IGFBP3, IGF1 (insulin-like growth factor I), and IGF2 (insulin-like growth factor II) can be altered by dietary modifications (here, long-term caloric restriction in Welsh Pony mares).
This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
, IGF-binding protein 3
, acid stable subunit of the 140 K IGF complex
, binding protein 29
, binding protein 53
, growth hormone-dependent binding protein
, insulin-like growth factor-binding protein 3
, insulin-like growth factor-binding protein (IGF-BP3)
, insulin-like growth factor binding protein-3
, insulin-like growth factor binding protein 3