Aperçu des produits pour anti-RAMP3 (RAMP3) Anticorps

Mouse (Murine) Receptor (G Protein-Coupled) Activity Modifying Protein 3 (RAMP3) interaction partners

1. the cardiovascular response of Ramp1 (Montrer RAMP1 Anticorps)(-/-), Ramp2 (Montrer RAMP2 Anticorps)(+/-), Ramp3(-/-), Ramp1 (Montrer RAMP1 Anticorps)(-/-)/Ramp3(-/-) double-knockout (dKO), and Calcrl (Montrer CALCRL Anticorps)(+/-) mice to AM and CGRP (Montrer CALCA Anticorps) were compared to wildtype mice.These results suggest that the hypotensive effect of AM is primarily mediated through the CLR (Montrer CALCR Anticorps)/RAMP1 (Montrer RAMP1 Anticorps) heterodimer, but that AM signaling via CLR (Montrer CALCR Anticorps)/RAMP2 (Montrer RAMP2 Anticorps) and CLR (Montrer CALCR Anticorps)/RAMP3 also contributes to some hypotensive action.

2. RAMP3 regulates drainage through lymphatic vessels.

3. G-protein-coupled receptor 30 (Montrer GPER Anticorps) interacts with receptor activity-modifying protein 3 and confers sex-dependent cardioprotection.

4. Data show that mechanical ventilation reduced the expression of receptor activity-modifying protein RAMP3, but not of intermedin (IMD (Montrer ADM2 Anticorps)), calcitonin receptor-like receptor (CRLR (Montrer CALCRL Anticorps)), and RAMP1 (Montrer RAMP1 Anticorps) and RAMP2 (Montrer RAMP2 Anticorps).

5. these data demonstrate a sex-dependant, cardioprotective role of RAMP3 in the setting of chronic hypertension.

6. role in cell surface expression of CRLR (Montrer CALCRL Anticorps)/RAMP heterodimeric receptors

7. RAMP2 (Montrer RAMP2 Anticorps) and RAMP3 have distinct physiological functions throughout embryogenesis, adulthood, and old age

8. tight regulation of WAP gene expression parallels variations in the chromatin structure and DNA methylation (Montrer HELLS Anticorps) profile throughout the Ramp3-WAP-Tbrg4 (Montrer TBRG4 Anticorps) locus.

Human Receptor (G Protein-Coupled) Activity Modifying Protein 3 (RAMP3) interaction partners

1. interaction of RAMP2 (Montrer RAMP2 Anticorps) or RAMP3 with CLR (Montrer DCLK3 Anticorps) induces conformational variation in the juxtamembrane region, yielding distinct binding pockets, probably via an allosteric mechanism.

2. the AM system is widely expressed in human thymus from newborns; both AM1 receptor components CLR (Montrer DCLK3 Anticorps) and RAMP2 (Montrer RAMP2 Anticorps), but not RAMP3, are not associated with the plasma membrane of TECs and thymocytes but are located intracellularly, notably in the nucleus

3. Data suggest isoforms of RAMP modulate accessibility of peptides to residues situated on CALCRL (calcitonin receptor-like receptor (Montrer CALCRL Anticorps)) N-terminal domain; RAMP3/RAMP2 (Montrer RAMP2 Anticorps)/RAMP1 (Montrer RAMP1 Anticorps) appear to alter accessibility of specific residues at CALCRL (Montrer CALCRL Anticorps)-RAMP interface.

4. The expression of RAMP3 is downregulated in the fetal lung with increasing gestational age.

5. the RAMP3 TMD (Montrer TTN Anticorps) participates in the negative regulation of CLR (Montrer DCLK3 Anticorps)/RAMP3 internalization.

6. Data show that LOXL2 (Montrer LOXL2 Anticorps) and RAMP3 are strongly coexpressed in human colon, breast, and gastric carcinomas but not in normal colon or gastric epithelial cells.

7. This study provides insight into the role of three amino acid changes in human RAMP3.

8. Morphological fluorescence techniques, bioluminescence resonance energy transfer, and bimolecular fluorescence complementation analysis demonstrate that the secretin receptor (Montrer SCTR Anticorps) associates specifically with RAMP3, but not with RAMP1 (Montrer RAMP1 Anticorps) or RAMP2 (Montrer RAMP2 Anticorps).

9. Receptor activity modifying proteins interaction with human and porcine calcitonin receptor-like receptor (CRLR (Montrer CALCRL Anticorps)) in HEK (Montrer EPHA3 Anticorps)-293 cells

10. results show the presence of calcitonin receptor-like receptor (Montrer CALCRL Anticorps) and receptor activity-modifying proteins in middle meningeal, middle cerebral, pial, and superficial temporal vessels

Cow (Bovine) Receptor (G Protein-Coupled) Activity Modifying Protein 3 (RAMP3) interaction partners

1. Data indicate that adrenomedullin (Montrer ADM Anticorps) mRNA and protein signal were only found in trophoblast binucleate cells (BNCs), whereas those of CRLR (Montrer CALCRL Anticorps), RAMP2 (Montrer RAMP2 Anticorps) and RAMP3 were detected in cotyledonary villous and caruncular epithelial cells.