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anti-Human MUC1 Anticorps:
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Human Monoclonal MUC1 Primary Antibody pour ELISA, ICC - ABIN266893
Dalziel, Whitehouse, McFarlane, Brockhausen, Gschmeissner, Schwientek, Clausen, Burchell, Taylor-Papadimitriou: The relative activities of the C2GnT1 and ST3Gal-I glycosyltransferases determine O-glycan structure and expression of a tumor-associated epitope on MUC1. dans The Journal of biological chemistry 2001
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Human Monoclonal MUC1 Primary Antibody pour IHC (f), IHC (fro) - ABIN2689099
Agrawal, Schatz: RAG1 and RAG2 form a stable postcleavage synaptic complex with DNA containing signal ends in V(D)J recombination. dans Cell 1997
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Human Polyclonal MUC1 Primary Antibody pour ICC, IF - ABIN5631320
Nallasamy, Li, Bagchi, Bagchi: Msx homeobox genes critically regulate embryo implantation by controlling paracrine signaling between uterine stroma and epithelium. dans PLoS genetics 2012
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Human Monoclonal MUC1 Primary Antibody pour ICC, FACS - ABIN335355
Gourevitch, von Mensdorff-Pouilly, Litvinov, Kenemans, van Kamp, Verstraeten, Hilgers: Polymorphic epithelial mucin (MUC-1)-containing circulating immune complexes in carcinoma patients. dans British journal of cancer 1995
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Human Monoclonal MUC1 Primary Antibody pour FACS, IHC (fro) - ABIN2479333
Gill: Brittle diabetes: a report of the First International Conference on Brittle Diabetes. dans Diabetic medicine : a journal of the British Diabetic Association 1992
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Human Monoclonal MUC1 Primary Antibody pour IHC (fro), IHC (p) - ABIN2479332
Kennedy, Darne, Cohn, Price, Davies, Blumsohn, Griffiths: Human chorionic gonadotropin may not be responsible for thyroid-stimulating activity in normal pregnancy serum. dans The Journal of clinical endocrinology and metabolism 1992
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Human Monoclonal MUC1 Primary Antibody pour IHC (fro), IHC (p) - ABIN966067
Hilkens, Buijs, Hilgers, Hageman, Calafat, Sonnenberg, van der Valk: Monoclonal antibodies against human milk-fat globule membranes detecting differentiation antigens of the mammary gland and its tumors. dans International journal of cancer. Journal international du cancer 1984
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Cow (Bovine) Polyclonal MUC1 Primary Antibody pour ICC, IF - ABIN4336040
Rosa, Osorio, Trevisi, Yanqui-Rivera, Estill, Bionaz: 2,4-Thiazolidinedione Treatment Improves the Innate Immune Response in Dairy Goats with Induced Subclinical Mastitis. dans PPAR research 2017
Cow (Bovine) Polyclonal MUC1 Primary Antibody pour IHC, WB - ABIN2776820
Braun, Sponder, Pieper, Aschenbach, Deiner: GABA selectively increases mucin-1 expression in isolated pig jejunum. dans Genes & nutrition 2015
Human Monoclonal MUC1 Primary Antibody pour IHC (f), IHC (fro) - ABIN2689100
Devine, Birrell, Whitehead, Harada, Xing, McKenzie: Expression of MUC1 and MUC2 mucins by human tumor cell lines. dans Tumour biology 1993
High MUC1 expression is associated with breast cancer metastasis.
These results revealed that serum WFA-sialylated MUC1 was associated with histological features of hepatocellular carcinoma and recurrence after curative therapy.
this study shows that basaloid squamous cell carcinoma and basal cell carcinoma of the head and neck can be readily distinguished by a limited panel consisting primarily of EMA, and supported by SOX2 and p16
In the in vitro tests, JFD-WS effectively inhibited HUVEC proliferation, migration, tube formation and VEGFR2 (Montrer KDR Anticorps) phosphorylation. Additionally, JFD-WS inhibited the formation of blood vessels in chick chorioallantoic membrane. While inhibiting the xenograft tumor growth in experimental mice, JFD-WS decreased the plasma MUC1 levels
Quercetin suppressed breast cancer stem cell proliferation, self-renewal, and invasiveness. It also lowered the expression levels of proteins related to tumorigenesis and cancer progression, such as aldehyde dehydrogenase 1A1 (Montrer ALDH1A1 Anticorps), C-X-C chemokine receptor type 4 (Montrer CXCR4 Anticorps), mucin 1, and epithelial cell adhesion molecules.
the proposed ECL immunosensor opened a new era for sensitive CA15-3 evaluation and offered a promising platform for clinical breast cancer diagnostics.
MUC1-mediated nucleotide metabolism plays a key role in facilitating radiation resistance in pancreatic cancer and targeted effectively through glycolytic inhibition
These findings indicate that decitabine intensifies MUC1-C inhibition induced redox imbalance and provides a novel combination of targeted and epigenetic agents for patients with Cutaneous T-cell lymphoma
silencing MUC1 expression inhibited migration and invasion, and induced apoptosis of PANC-1 cells via downregulation of Slug and upregulation of Slug dependent PUMA (Montrer BBC3 Anticorps) and E-cadherin (Montrer CDH1 Anticorps) expression.
this paper shows the role of IgG and Fcgamma receptor genes in endogenous antibody responses to mucin 1 in a large multiethnic cohort of Brazilian patients with breast cancer
The results indicate that Muc1 gene is significantly associated with litter size in pigs.
The epiblast expressed epithelial markers, MUC1 and E-CADHERIN (Montrer CDH1 Anticorps), and the pluripotency markers, DNMT3B (Montrer DNMT3B Anticorps) and CRIPTO (Montrer TDGF1 Anticorps).
Endometrial expressions of MUC1 and cytokine genes differed among normal, fertile versus diseased, and subfertile dairy cows.
Bovine Muc1 prevents binding of bacteria to human intestinal cells and may have a role in preventing the binding of common enteropathogenic bacteria to human intestinal epithelial surfaces.
concluded that bovine Muc1 protein is probably an inducible innate immune effector and an important component of the first line of defense against bacterial invasion of epithelial surfaces
this study implicates the MUC1 as a critical and dynamic component of the innate host response that limits the severity of influenza and provides the foundation for exploration of MUC1 in resolving inflammatory disease
Tumor growth delays observed by tumor irradiation combined with MVA (Montrer MYO5A Anticorps)-MUC1-IL-2 (Montrer IL2 Anticorps) vaccine were significantly more prolonged than those observed by vaccine, radiation, or radiation with MVA (Montrer MYO5A Anticorps) empty vector.
Muc1 has anti-fibrotic properties in the mouse lung.
our data suggest a novel molecular mechanism by which tMUC1 may modulate NRP1 (Montrer NRP1 Anticorps)-dependent VEGFR (Montrer KDR Anticorps) signaling in PDA cells.
Low expression of MUC1 is associated with lung carcinogenesis.
Using an extensive collection of novel murine cell lines we have identified distinct roles for Kras and Pten on MUC1 and EMT (Montrer ITK Anticorps) in vivo and in vitro. The data has implications for future design of combination therapies targeting Kras mutations, Pten deletions and MUC1 vaccines.
Gp91phox (Montrer CYBB Anticorps) NADPH oxidase (Montrer NOX1 Anticorps) modulates litter size by up-regulating mucin1 expression in the uterus of mice.
In summary, we have demonstrated that MUC1 on immune cells is a novel regulator of the NLRP3 (Montrer NLRP3 Anticorps) inflammasome, and propose this is mediated by an interaction with signalling components at the cytoplasmic domains of TLRs that involves inhibition of IRAK4 (Montrer IRAK4 Anticorps) activation.
MUC1 regulates IL-1beta (Montrer IL1B Anticorps) secretion induced by the NLRP3 (Montrer NLRP3 Anticorps)-activating bacteria Haemophilus influenzae but not bacteria that activate other inflammasomes.
Muc1 protection during acute kidney injury proceeds by enhancing both the HIF-1 (Montrer HIF1A Anticorps) and beta-catenin (Montrer CTNNB1 Anticorps) protective pathways.
This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.
, H23 antigen
, breast carcinoma-associated antigen DF3
, cancer antigen 15-3
, carcinoma-associated mucin
, krebs von den Lungen-6
, mucin 1, transmembrane
, peanut-reactive urinary mucin
, polymorphic epithelial mucin
, tumor associated epithelial mucin
, tumor-associated epithelial membrane antigen
, tumor-associated mucin
, endometrial mucin-1
, epithelial mucin