anti-MUC1 Anticorps

Profil protéine

This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.

Alternative names and synonyms associated with MUC1

• mucin 1, cell surface associated (MUC1) anticorps
• mucin 1, cell surface associated (Muc1) anticorps
• mucin 1, transmembrane (Muc1) anticorps

• CA 15-3 anticorps
• CD227 anticorps
• EMA anticorps
• H23AG anticorps
• KL-6 anticorps
• Afficher tous les alias de synonymes
• MAM6 anticorps
• MCKD1 anticorps
• Muc-1 anticorps
• MUC-1/SEC anticorps
• MUC-1/X anticorps
• MUC1/ZD anticorps
• PEM anticorps
• PEMT anticorps
• PUM anticorps

Protein level used designations for MUC1

DF3 antigen , H23 antigen , breast carcinoma-associated antigen DF3 , cancer antigen 15-3 , carcinoma-associated mucin , episialin , krebs von den Lungen-6 , mucin 1, transmembrane , mucin-1 , peanut-reactive urinary mucin , polymorphic epithelial mucin , tumor associated epithelial mucin , tumor-associated epithelial membrane antigen , tumor-associated mucin , endometrial mucin-1 , epithelial mucin , MUC-1 , Mucin1