anti-AFT1 Anticorps

Profil protéine

This gene encodes an activating transcription factor, which belongs to the ATF subfamily and bZIP (basic-region leucine zipper) family. It influences cellular physiologic processes by regulating the expression of downstream target genes, which are related to growth, survival, and other cellular activities. This protein is phosphorylated at serine 63 in its kinase-inducible domain by serine/threonine kinases, cAMP-dependent protein kinase A, calmodulin-dependent protein kinase I/II, mitogen- and stress-activated protein kinase and cyclin-dependent kinase 3 (cdk-3). Its phosphorylation enhances its transactivation and transcriptional activities, and enhances cell transformation. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in angiomatoid fibrous histiocytoma and clear cell sarcoma. This gene has a pseudogene on chromosome 6.

Alternative names and synonyms associated with AFT1

• activating transcription factor 1 (atf1) anticorps
• activating transcription factor 1 (ATF1) anticorps
• activating transcription factor 1 (MGC85066) anticorps
• activating transcription factor 1 L homeolog (atf1.L) anticorps
• activating transcription factor 1 (Atf1) anticorps

• Atf-1 anticorps
• ATF1 anticorps
• EWS-ATF1 anticorps
• FUS/ATF-1 anticorps
• TREB36 anticorps
• Afficher tous les alias de synonymes
• wu:fc92c07 anticorps
• zgc:64099 anticorps

Protein level used designations for AFT1

activating transcription factor 1 , cyclic AMP-dependent transcription factor ATF-1 , cAMP-dependent transcription factor ATF-1 , TCR-ATF1