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Aperçu des produits pour anti-NR2C1 (NR2C1) Anticorps

Full name:: anti-Nuclear Receptor Subfamily 2, Group C, Member 1 Anticorps (NR2C1)

Chez www.anticorps-enligne.fr sont 132 Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1) Anticorps de 21 de différents fournisseurs disponibles. De plus, nous expédions NR2C1 Protéines (11) et NR2C1 Kits (3) et beaucoup plus de produits pour cette protéine. Un total de 156 NR2C1 produits sont actuellement listés.

Synonymes:: 80.3, 4831444H07Rik, DKFZp468M0512, dor2, Eenr, NR2C1, Psg4, si:dkey-183c16.2, Tr2, TR2-11, xDOR2, zgc:110672

afficher tous les anticorps	Gène	GeneID	UniProt
	NR2C1	7181	P13056
	NR2C1	22025	Q505F1
	NR2C1	252924	Q8VIJ4
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Pathways pertinentes pour anti-NR2C1 Anticorps

Steroid Hormone Mediated Signaling Pathway

Plus produit pour NR2C1 Anticorps

anti-NR2C1 Anticorps mieux référencés

Human Polyclonal NR2C1 Primary Antibody pour IP, WB - ABIN4361558 : Olivares, Han, Soto, Flattery, Marini, Molemma, Haider, Escher, DeAngelis, Haider: The nuclear hormone receptor gene Nr2c1 (Tr2) is a critical regulator of early retina cell patterning. dans Developmental biology 2017 (PubMed)

Plus d’anticorps contre NR2C1 partenaires d’interaction

Human Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1) interaction partners

DRED is a 540 kDa complex containing the nuclear orphan receptors TR2 and TR4, which form a heterodimer that binds to the epsilon and gamma globin promoter DR1 sites. TR2 & 4 mRNAs are expressed at all stages of murine and human erythropoiesis.
TR2 that may exert an important repressor in regulating ER activity in mammary glands.
TR2 and TR4 can have distinct functions. Existence of differential and bi-directional regulation between PPAR alpha and TR2/TR4. Possible roles in PPAR alpha signaling pathway in human keratinocytes.
TR2 may function as a negative modulator to suppress androgen receptor function in prostate cancer. Further studies on how to control TR2 function may result in the ability to modulate AR function in prostate cancer.
The NF1-A transcription factor plays an important role in the transcriptional activation of the TR2 gene expression via a promoter activating cis-element.

Mouse (Murine) Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1) interaction partners

This study supports a role for Nr2c1 in defining the biphasic period of retinal development and specifically influencing the early phase of retinal cell fate.
Nr2c1 may be a candidate for mediating parallel adaptive changes in cranial neural sensory specializations such as the olfactory epithelium, retina and mystacial vibrissae and in non-neural craniofacial features including teeth
TR2/TR4 expression in sickle cell disease mice confers enhanced fetal hemoglobin synthesis and alleviated disease phenotypes
in adult erythroid cells, TR2/TR4 bind to the embryonic beta-type globin promoters but not to the adult beta-globin promoter.
TR2 may not play essential roles in spermatogenesis and normal testis development, function, and maintenance. Alternatively, the roles of TR2 may be redundant and could be played by other close members of the nuclear receptor superfamily (TR2 receptor)
DRED is a 540 kDa complex containing the nuclear orphan receptors TR2 and TR4, which form a heterodimer that binds to the epsilon and gamma globin promoter DR1 sites. TR2 & 4 mRNAs are expressed at all stages of murine and human erythropoiesis.
These results suggest a SUMOylation-dependent partitioning and differential coregulator recruitment contribute to the maintenance of a homeostatic supply of activating, Tr2, thus fine-tuning Oct4 expression and regulating stem-cell proliferation.
Silencing of the embryonic and fetal beta globin genes is delayed in erythroid cells of Tr2 and Tr4 null mutant mice, whereas in transgenic mice expressing dominant-negative TR4 (dnTR4), human embryonic epsilon-globin is activated in erythroid cells.
TR2 and TR4 orphan nuclear receptors repress Gata1 transcription.
Retinoic acid-stimulated sequential phosphorylation, PML recruitment, and SUMOylation of nuclear receptor TR2 to suppress Oct4 expression
Possible roles for TR2 and TR4 in early embryonic development by regulating key genes involved in stem cell self-renewal, commitment, and differentiation.
This is the first report identifying a deacetylase-independent function for HDAC3, which serves as a specific carrier molecule that targets a specifically phosphorylated protein to promyelocytic leukemia (PML) nuclear bodies.

NR2C1 profil antigène

Antigen Summary

This gene encodes a nuclear hormone receptor characterized by a highly conserved DNA binding domain (DBD), a variable hinge region, and a carboxy-terminal ligand binding domain (LBD) that is typical for all members of the steroid/thyroid hormone receptor superfamily. This protein also belongs to a large family of ligand-inducible transcription factors that regulate gene expression by binding to specific DNA sequences within promoters of target genes. Multiple alternatively spliced transcript variants have been described, but the full-length nature of some of these variants has not been determined.

Alternative names and synonyms associated with NR2C1

nuclear receptor subfamily 2 group C member 1 (NR2C1) anticorps
nuclear receptor subfamily 2, group C, member 1 (nr2c1) anticorps
nuclear receptor subfamily 2 group C member 1 S homeolog (nr2c1.S) anticorps
nuclear receptor subfamily 2, group C, member 1 (NR2C1) anticorps
nuclear receptor subfamily 2, group C, member 1 (Nr2c1) anticorps

80.3 anticorps
4831444H07Rik anticorps
DKFZp468M0512 anticorps
dor2 anticorps
Eenr anticorps
NR2C1 anticorps
Psg4 anticorps
si:dkey-183c16.2 anticorps
Tr2 anticorps
TR2-11 anticorps
xDOR2 anticorps
zgc:110672 anticorps

Protein level used designations for NR2C1

, , , , , , , , , , , , , , , , , , , nuclear receptor subfamily 2, group C, member 1 Nuclear receptor subfamily 2 group C member 1 TR2 nuclear hormone receptor nuclear receptor subfamily 2 group C member 1 nuclear receptor subfamily 2, group C isoform orphan nuclear receptor TR2 DOR2-A developmental orphan receptor 2 developmental orphan receptor 2-A nuclear receptor subfamily 2 group C member 1-A orphan nuclear receptor TR2-A testicular receptor 2-A xDOR2-A 80-3 cNDA early embryonic nuclear receptor mTR2 nuclear receptor subfamily 2, group H, member 1 orphan receptor, TR2-11 testicular receptor 2 pregnancy specific beta-1-glycoprotein 4

GENE ID	SPECIES
467096	Pan troglodytes
100052073	Equus caballus
100174333	Pongo abelii
7181	Homo sapiens
553649	Danio rerio
399361	Xenopus laevis
373913	Gallus gallus
611980	Canis lupus familiaris
511407	Bos taurus
22025	Mus musculus
252924	Rattus norvegicus

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Show all anti-Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1) Anticorps with Pubmed References

Human Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1) interaction partners

Mouse (Murine) Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1) interaction partners

Antigen Summary

Alternative names and synonyms associated with NR2C1

Protein level used designations for NR2C1