Aperçu des produits pour anti-Retinoic Acid Receptor gamma (RARG) Anticorps

Human Retinoic Acid Receptor, gamma (RARG) interaction partners

1. In prostate cancer cells, miR-96 directly regulated RARgamma expression and function. miR-96 targets a RARgamma network to govern AR signaling, PCa progression and disease outcome.

2. Study reports that retinoic acid receptor-gamma (RARgamma) is a negative regulator of p53 signaling and thus extend the oncogenic potential of RARgamma to a new role in controlling the balance between AKT and p53.

3. the cytoplasmic retinoic acid receptor gamma (RARgamma) controls receptor-interacting protein kinase 1 (RIP1)-initiated cell death when cellular inhibitor of apoptosis (cIAP) activity is blocked.

4. Results show that RARgamma expression is significantly upregulated in human hepatocellular carcinoma (HCC) tissues and demonstrate that RARgamma could promote HCC invasion and metastasis by regulating E-cadherin reduction.

5. Dual small interfering RNA (siRNA) silencing of RARalpha and RARgamma reversed RA blockade of P4-induced CK5. Using promoter deletion analysis, we identified a region 1.1 kb upstream of the CK5 transcriptional start site that is necessary for P4 activation and contains a putative progesterone response element (PRE

6. Our study is the first to report that treatment with a RARgamma specific agonist augments cellular adhesion to alpha5beta1 integrin substrates, increases cell surface levels of the beta1 integrin subunit, and dampens cellular proliferation in a time and concentration dependent manner in a human erythroleukemia cell line

7. Loss of RARG expression is associated with Colorectal Tumorigenesis and Metastasis.

8. RARgamma might serve as a potential therapeutic target for chemoresistant colorectal cancer patients.

9. A nonsynonymous variant in RARG is highly associated with anthracycline-induced cardiotoxicity in childhood cancers.

10. deregulation of the retinoid/rexinoid signaling pathway has a major role and may represent a potential therapeutic target for NUP98-RARG-mediated transformation

11. The current status of knowledge indicates that there might be inter- or overlapping actions between PPARg and RARs, and there might be an association of PPARg/RARs(RARa, RARb, and RARg) with renal diseases

12. RARgamma in concert with ATRA regulates protein levels of CDK1 and its subcellular localization.

13. RARG plays an important role in the proliferation, metastasis, and chemoresistance of cholangiocarcinoma through simultaneous activation of the Akt/NF-kappaB and Wnt/beta-catenin pathways.

14. Low RARgamma expression is associated with advanced gastric cancer.

15. Evidence that the retinoic acid receptor gamma plays a major role in the regulation of the human prostatic transglutaminase gene.

16. findings demonstrate that signaling through RARs has critical roles in molecular reprogramming and that the synergistic interaction between Rarg and Lrh1 directs reprogramming toward ground-state pluripotency

17. results suggest that a RARgamma-dependent functional crosstalk is present between the retinoic acid and BMP2 signaling to induce osteogenic transdifferentiation in myoblastic C2C12 cells

18. One variant in the RARA gene (rs12051734), three variants in the RARB gene (rs6799734, rs12630816, rs17016462), and one variant in the RARG gene (rs3741434) were found to be statistically significant at p < 0.05 as risk factors for meningomyelocele.

19. Microbiota are required for the generation of both IL-17-positive and Foxp3-positive, retinoic acid-related orphan receptor gamma-positive transgenic T cell subsets in the intestinal lamina propria.

20. PARgamma expressions are decreased in PBMC and SWAT of obese subjects in weight gain.

Mouse (Murine) Retinoic Acid Receptor, gamma (RARG) interaction partners

1. RARgamma signaling is required for the differentiation of hypertrophic chondrocytes, with differential cooperation with p38 MAPK.

2. the RAR:RXR and LXR:RXR-mediated transcriptional program in embryonic stem cells, neural progenitors and terminally differentiated neurons, is reported.

3. This study used CRISPR technology to introduce biallelic frameshift mutations in RAR alpaha, RAR beta, and RAR gamma, thereby abrogating all RAR functions in murine embryonic stem cells. RAR-null cells display no changes in transcripts in response to All-trans-retinoic acid (RA), demonstrating that the RARs are essential for the regulation of all transcripts in murine embryonic stem cells in response to RA.

4. RARalpha and RARgamma reciprocally control K5(+) progenitor cell proliferation and distribution in the developing submandibular salivary epithelium in a cell cycle-dependent manner while regulating lumenization independently of keratinizing differentiation

5. these studies show that RARgamma is a regulator of B and T lymphopoiesis

6. the reprogramming of epiblast stem cells into embryonic stem cell-like cells also requires low levels of retinoic acid (RA), which can modulate Wnt signalling through physical interactions of RARs with beta-catenin.

7. Data show that retinoic acid receptor gamma (RARgamma)-proto-oncogene protein c-fos (c-Fos)-PPARgamma2 (PPARgamma2) signaling rather than reactive oxygen species generation is critical for all-trans retinoic acid (ATRA)-inhibited adipocyte differentiation.

8. RARgamma plays key roles in the differentiation competence of NGN3+ cells in response to retinoic acid during mouse spermatogenesis.

9. The results indicate a physiological role for RARgamma as a negative regulator of osteoclastogenesis in vivo and in vitro, and reveal distinct influences of RARalpha and RARgamma in bone structure regulation.

10. this study shows that the combination of Rarg and Nr5a2 rapidly promote the iN cell maturation within 1 week and greatly facilitate the conversion with neuronal purities of approximately 50% and yields of >130%.

11. Data indicate that all three retinoic acid receptor isoforms RARalha, RARbeta and RARgamma are expressed in naive CD8+ T cells, as well as CD8+ T cells activated for 48 or 72 h.

12. erythroid-specific RAR function is dispensable for erythropoiesis and RARgamma plays an erythroid extrinsic role in erythropoiesis.

13. RARG plays an important role in the proliferation, metastasis, and chemoresistance of cholangiocarcinoma through simultaneous activation of the Akt/NF-kappaB and Wnt/beta-catenin pathways.

14. Data indicate that male germ cell specific miR-34c might be pivotal in embryonic stem cells (ESCs) differentiation into male germ cells through its target retinoic acid receptor gamma (RARg).

15. RARG cell-autonomously transduces, in undifferentiated spermatogonia of adult testes, a RA signal critical for spermatogenesis.

16. RARalpha and RARgamma are present in pluripotent and differentiating mEC and mES cells and suggest that the expression of these proteins is dynamic.

17. findings demonstrate that signaling through RARs has critical roles in molecular reprogramming and that the synergistic interaction between Rarg and Lrh1 directs reprogramming toward ground-state pluripotency

18. Data show that RARgamma is required for deposition of H2A.Z and Suz12 at RA target genes, and that in embryonic stem cells both RARgamma and Suz12 exist in a multi-protein complex in the absence of ligand.

19. In the absence of retinoic acid (RA), vinexinbeta does not occupy RARgamma target gene promoters and sequesters nonphosphorylated RARgamma out of promoters

20. RARgamma regulates CB(1)R expression and is thus involved in the control of hepatic fat metabolism by endocannabinoids