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anti-Human RORA Anticorps:
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Human Polyclonal RORA Primary Antibody pour ICC, IF - ABIN4350939
Benderdour, Fahmi, Beaudet, Fernandes, Shi: Nuclear receptor retinoid-related orphan receptor α1 modulates the metabolic activity of human osteoblasts. dans Journal of cellular biochemistry 2011
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Cow (Bovine) Polyclonal RORA Primary Antibody pour WB - ABIN2776008
Tordjman, Leroyer, Chauvet, Quette, Chauvet, Tomkiewicz, Chapron, Barouki, Forest, Aggerbeck, Antoine: Cytosolic aspartate aminotransferase, a new partner in adipocyte glyceroneogenesis and an atypical target of thiazolidinedione. dans The Journal of biological chemistry 2007
CYP11A1 (Montrer CYP11A1 Anticorps)- derived hydroxyvitamin D derivatives as "inverse" agonists on ROR-alpha and ROR-gamma.
The expression RORalpha is significantly elevated under hypoxic conditions in keratinocytes in an HIF-1alpha (Montrer HIF1A Anticorps) dependent manner.
Retinoid-related orphan receptor alpha-regulated development of the mouse cerebellum has a distinct critical period for (1) lengthening Purkinje cell (PC) primary dendrite stems and the eventual increase in the thickness of the molecular layer and (2) the establishment of mGluR (Montrer GRM8 Anticorps) signaling and associated removal of surplus climbing fibers from PCs.
findings strongly suggest that CLDND1 is a direct RORalpha target
TRIB3 (Montrer TRIB3 Anticorps) promotes acute promyelocytic leukemia (Montrer PML Anticorps) progression through stabilization of the oncoprotein PML (Montrer PML Anticorps)-RARalpha (Montrer RARA Anticorps) and inhibition of p53 (Montrer TP53 Anticorps)-mediated senescence.
Retinoid-related orphan receptor alpha (RORalpha) reduction occurs in gastric cancer leading to the survival of tumor cells, which is attenuated by AMP-activated protein kinase (AMPK (Montrer PRKAA2 Anticorps)), therefore, both RORalpha and AMPK (Montrer PRKAA1 Anticorps) are potential targets for the intervention and therapy in gastric carcinoma.
the RAR-related orphan receptor-a gene (RORA) and the Peroxisome Proliferator-Activated Receptor Gamma (Montrer PPARG Anticorps), Coactivator 1 Alpha gene (PPARGC1A or PGC-1alpha) were significantly associated with the Li response. Our results suggest genetic associations between Li response and these two close biological partners: PPARGC1A and RORA involved in circadian rhythms and bioenergetics processes in Li response
The present study is to determine if any relation exists between RORA rs11639084 and rs4774388 gene polymorphisms on the individual susceptibility of multiple sclerosis.
Association between RORA gene polymorphisms and the DSM-5 posttraumatic stress disorder symptoms in male earthquake survivors in China.
The RORA intronic SNP rs11632098 was associated with greater odds of reporting depressive symptoms in older adults.
study reports cloning and expression pattern of zebrafish ROR alpha orthologues rora1 and rora2; both rora1 and rora2 are spatially expressed in the retina and tectum; expression of rora2 was further observed in the cerebellum
RORalpha/gamma controls circadian expression of Insig2 (Montrer INSIG2 Anticorps), which keeps feeding-induced SREBP1c (Montrer SREBF1 Anticorps) activation under check
RORalpha induces KLF4 (Montrer KLF4 Anticorps) mediated Kupffer cells polarization and protects against NASH (Montrer SAMSN1 Anticorps).
RORalpha/gamma are important therapeutic targets for cutaneous inflammation; RORa and RORg (Montrer RORC Anticorps) have roles in inflammation in mouse models of atopic dermatitis and acute irritant dermititis
Data demonstrated that the circadian rhythm of testosterone synthesis in TM3 (Montrer TPM1 Anticorps) cells was disturbed following Fen treatment as evidenced by changes in the circadian rhythmicity of core clock genes (Bmal1 (Montrer ARNTL Anticorps), Rev-erbalpha (Montrer NR1D1 Anticorps), Roralpha).
RORalpha inhibits PPARgamma (Montrer PPARG Anticorps)-mediated transcriptional activity by interacting with HDAC3 (Montrer HDAC3 Anticorps) and competing for the promoters of lipogenic genes.
that retinoic acid receptor-related orphan receptor alpha is a novel transcriptional regulator of SEMA3E (Montrer SEMA3E Anticorps)-mediated neurovascular coupling in pathological retinal angiogenesis
The deficiency of LXRalpha (Montrer NR1H3 Anticorps) decreased glucose uptake after MI, resulting in a metabolic shift that suppressed glucose metabolism, which was in association with adverse cardiac remodeling.
Data suggest that inflammatory response in macrophages, white adipocytes, and white adipose tissue in obese mice, includes up-regulation of expression of Rora; in adipose tissue, overexpression of Rora or treatment with Rora agonist enhances expression of cytokines, promotes macrophage infiltration, up-regulates expression of genes involved in ER stress response, and enhances signaling seen in unfolded protein response.
these findings reveal that RORalpha regulates macrophage M2 polarization via activation of AMPKalpha (Montrer GRK4 Anticorps)
The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Four transcript variants encoding different isoforms have been described for this gene.
nuclear receptor ROR-alpha
, RAR-related orphan receptor A
, RAR-related orphan receptor alpha
, nuclear receptor RZR-alpha
, nuclear receptor subfamily 1 group F member 1
, retinoic acid receptor-related orphan receptor alpha
, retinoid-related orphan receptor alpha
, thyroid hormone nuclear receptor alpha variant 4
, transcription factor RZR-alpha
, retinoid-related orphan receptor alpha 2
, retinoid-related orphan receptor-alpha