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anti-Human Adenylate Kinase 1 Anticorps:
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Human Polyclonal Adenylate Kinase 1 Primary Antibody pour ELISA, WB - ABIN544965
Toren, Brok-Simoni, Ben-Bassat, Holtzman, Mandel, Neumann, Ramot, Rechavi, Kende: Congenital haemolytic anaemia associated with adenylate kinase deficiency. dans British journal of haematology 1994
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Hamster Polyclonal Adenylate Kinase 1 Primary Antibody pour IHC (p), ELISA - ABIN544966
Zuffardi, Caiulo, Maraschio, Tupler, Bianchi, Amisano, Beluffi, Moratti, Liguri: Regional assignment of the loci for adenylate kinase to 9q32 and for alpha 1-acid glycoprotein to 9q31-q32. A locus for Goltz syndrome in region 9q32-qter? dans Human genetics 1989
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a role for ADK and the S-adenosyl-L-methionine pathway in the control of root gravitropism and cap morphogenesis
Case Reports: first case of adenylate kinase deficiency in Indian population due to novel AK1 mutations (c.71A>G and c.413G>A) associated with nonspherocytic haemolytic anaemia without psychomotor impairment.
Studies indicate that the preferred substrate and phosphate donor of all adenylate kinases are AMP and ATP respectively.
Dysregulation of AMPK is both a pathogenic factor for these disorders in humans and a target for their prevention and therapy. [Review]
Ak(1)2-1 phenotype is more frequent in males conceived in the summer-autumn period than in those conceived in winter-spring, and this association depends on maternal Ak(1) phenotype.
identified hitherto unrecognized soluble forms of AK1 and NTPDase1/CD39 that contribute in the active cycling between the principal platelet-recruiting agent ADP and other circulating nucleotides
Data indicate that the neuronal adenylate kinase-1 (AK1) is induced by Abeta(42) to increase abnormal tau phosphorylation via AMPK-GSK3beta and contributes to tau-mediated neurodegeneration.
AK1 phenotypic activity is associated with birth weight and placental weight; these associations are greater in infants born at gestational age greater than 38 weeks.
Our findings suggest a reduced reproductive efficiency of women carrying the Ak(1)2-1 phenotype: this could have practical importance in predicting the probability of reproductive success in couples with RSA
The adipokine zinc-alpha2-glycoprotein activates AMP kinase in human primary skeletal muscle cells.
the correlation between blood glucose and glycated Hb in relation to AK1 and ACP1 polymorphism was studied.
how mutations found in 2 patients may affect enzyme structure and function; a compound heterozygote for 2 different missense mutations 118G>A(Gly40Arg) and 190G>A(Gly64Arg); a homozygote for either aspartic acid (Asp) 140 or 141
analysis of vascular endothelial ectoadenylate kinase and plasma membrane ATP synthase
The alpha-borano or alpha-H on PMEA and PMPA were detrimental to the activity of recombinant human AMP kinases 1
The data suggest that zygotes carrying AK1*2 allele are relatively protected from the damaging effects of smoking
Using shotgun mass spectrometry, we found this protein differentially expressed in the dorsolateral prefrontal cortex from patients with schizophrenia.
The sperm-associated proteins, P25b and adenylate kinase 1, are linked to detergent-resistant membrane of epididymal spermatozoa, but were exclusively associated with detergent-soluble material in ejaculated spermatozoa.
In addition to AK1 and AK2, which we previously demonstrated are present in outer dense fibers and mitochondrial sheath of the mouse sperm tail, we show that another AK, AK8, is present in a third flagellar compartment, the axoneme.
CaMKIalpha regulates AMP kinase-dependent, TORC-1-independent autophagy during lipopolysaccharide-induced acute lung neutrophilic inflammation.
AK1 is not involved in thiamine triphosphate synthesis in vivo
Deficiency of this enzyme induces molecular and structural adaptations to support muscle energy metabolism.
one of the consequences of M-CK and AK1 deficiency is hampered phosphoryl delivery to the actomyosin ATPase, resulting in a loss of contractile performance.
Skeletal muscle of mdx mice has reduced expression and enzymatic activity of adenylate kinase 1, but increased enzymatic activity of creatine kinase
The purpose of this study was to determine whether adenylate kinase 1 deficiency would result in sufficient ADP accumulation to be visible using (31)P-NMRS during the high energy demands of frequent in situ tetanic contractions.
AK1 in the flagellar accessory structures provides a mechanism to buffer the adenylate energy charge for sperm motility
Defective metabolic signaling in Ak1 gene knock-out hearts compromises post-ischemic coronary reflow.
Adenylate kinase-1 knockout mice have a normal capacity for contraction-mediated glucose uptake.
Creatine kinase (CK) and adenylate kinase (AK) are especially important in facilitating energy metabolism during very high energy demands.
Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate group among adinine nucleotides. Three isozymes of adenylate kinase have been identified in vertebrates, adenylate isozyme 1 (AK1), 2 (AK2) and 3 (AK3). AK1 is found in the cytosol of skeletal muscle, brain and erythrocytes, whereas AK2 and AK3 are found in the mitochondria of other tissues including liver and heart. AK1 was identified because of its association with a rare genetic disorder causing nonspherocytic hemolytic anemia where a mutation in the AK1 gene was found to reduce the catalytic activity of the enzyme.
, adenylate kinase-1
, adenylate kinase 5
, adenylate kinase 1
, adenylate kinase isoenzyme 1
, AK 1
, ATP-AMP transphosphorylase 1
, ATP:AMP phosphotransferase
, adenylate monophosphate kinase
, adenylate kinase 1, soluble
, cytosolic adenylate kinase
, Adenylate kinase isoenzyme 1