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NXF1 Produits

(Nuclear RNA Export Factor 1 (NXF1))
This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene shuttles between the nucleus and the cytoplasm and binds in vivo to poly(A)+ RNA. It is the vertebrate homologue of the yeast protein Mex67p. The encoded protein overcomes the mRNA export block caused by the presence of saturating amounts of CTE (constitutive transport element) RNA of type D retroviruses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008].

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Catégories NXF1 en vedette

NXF1 Anticorps

High quality antibodies with extensive validation data.

NXF1 Kits ELISA

Reliable ELISA kits for a wide range of species.

NXF1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

NXF1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse
Application WB, ELISA, IHC, IF, ICC
Validations
  • (4)
N° du produit ABIN6263783
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IP, IF, ICC
Validations
  • (3)
N° du produit ABIN2855276
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IF, ICC, IHC (p)
Validations
  • (3)
N° du produit ABIN2855280
Quantité 100 μL
Fiche technique Fiche technique

NXF1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN1116233
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
N° du produit ABIN511451
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Goat
Analytical Method Competition ELISA
Validations
N° du produit ABIN995473
Quantité 96 tests
Fiche technique Fiche technique

NXF1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
N° du produit ABIN1313263
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7124215
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1313265
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits NXF1

Yang, Huang, Li, Su, Shih: "Nuclear export of human hepatitis B virus core protein and pregenomic RNA depends on the cellular NXF1-p15 machinery." dans: PLoS ONE, Vol. 9, Issue 10, pp. e106683, (2014) (PubMed).

Bear, Tan, Zolotukhin, Tabernero, Hudson, Felber: "Identification of novel import and export signals of human TAP, the protein that binds to the constitutive transport element of the type D retrovirus mRNAs." dans: Molecular and cellular biology, Vol. 19, Issue 9, pp. 6306-17, (1999) (PubMed).

Braun, Rohrbach, Schmitt, Izaurralde: "TAP binds to the constitutive transport element (CTE) through a novel RNA-binding motif that is sufficient to promote CTE-dependent RNA export from the nucleus." dans: The EMBO journal, Vol. 18, Issue 7, pp. 1953-65, (1999) (PubMed).

Yoon, Lee, Seol, DeMaria, Rosenzweig, Jung: "Tap: a novel cellular protein that interacts with tip of herpesvirus saimiri and induces lymphocyte aggregation." dans: Immunity, Vol. 6, Issue 5, pp. 571-82, (1997) (PubMed).

Synonymes et noms alternatifs relatifs à NXF1

nuclear RNA export factor 1 (nxf1), nuclear RNA export factor 1 S homeolog (nxf1.S), nuclear RNA export factor 1 (NXF1), nuclear RNA export factor 1 (LOC100113601), nuclear RNA export factor 1 (Tsp_03999), nuclear RNA export factor 1 (Nxf1), Nuclear RNA export factor 1 (nxf-1), im:7156527, mex67, MEX67, Mex67, Mex67h, MGC82224, Mvb1, NXF1, tap, TAP, Tap, wu:fc12d06

Protein level used designations for NXF1

  • nuclear RNA export factor 1
  • small bristles
  • Nuclear RNA export factor 1
  • nuclear RNA export factor 1-like
  • mRNA export factor TAP
  • tip associating protein
  • tip-associated protein
  • tip-associating protein
  • Mex 67 homolog
  • modifier of vibrator 1
  • nuclear RNA export factor 1 homolog
  • tip associated protein
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