Profil protéine

This gene encodes a member of the bombesin-like family of gastrin-releasing peptides. Its preproprotein, following cleavage of a signal peptide, is further processed to produce either the 27 aa gastrin-releasing peptide or the 10 aa neuromedin C. These smaller peptides regulate numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation. These peptides are also likely to play a role in human cancers of the lung, colon, stomach, pancreas, breast, and prostate. Alternative splicing results in multiple transcript variants encoding different isoforms.

Alternative names and synonyms associated with Pro-Gastrin-Releasing Peptide (ProGRP)

• gastrin releasing peptide (GRP) anticorps

• BN anticorps
• GRP-10 anticorps
• preproGRP anticorps
• proGRP anticorps

Protein level used designations for ProGRP

bombesin , neuromedin C , pre-progastrin releasing peptide , prepro-GRP