ATP/GTP Binding Protein 1 (AGTPBP1) (C-Term) Peptide
AGTPBP1
Reactivité: Humain, Souris
Hôte: Synthetic
BP, WB
N° du produit ABIN1541167
150,78 €
Plus frais de livraison 40,00 € et TVA
100 μg
Destination:
France
Envoi sous 15 à 22 jours ouvrables
Aperçu rapide pour ATP/GTP Binding Protein 1 (AGTPBP1) (C-Term) Peptide (ABIN1541167)
Antigène
AGTPBP1
(ATP/GTP Binding Protein 1 (AGTPBP1))
Origine
Humain, Souris
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Séquence
- GMQPLMYSVQ EALNARPWWI RMGTDICYYK NHFSRSSVAA GGQKGKSYYT
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-Agtpbp1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- AGTPBP1 (ATP/GTP Binding Protein 1 (AGTPBP1))
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Sujet
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Agtpbp1 is a metallocarboxypeptidase that mediates deglutamylation of target proteins. It catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. It also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK. Agtpbp1 acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point glutamate, a process catalyzed by AGBL5/CCP5. Deglutamylation plays a key role in cerebellar Purkinje cell differentiation, accumulation of tubulin polyglutamylation causing neurodegeneration.
Alias Symbols: 1700020N17Rik, 2310001G17Rik, 2900054O13Rik, 4930445M19Rik, 5730402G09Rik, BB114605, CCP1, Nna1, mKIAA1035, nmf243, pcd
Protein Size: 1160 -
Poids moléculaire
- 128 kDa
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ID gène
- 67269
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NCBI Accession
- NM_023328, NP_075817
Antigène
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