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Ephrin B3 (EFNB3) (C-Term) Peptide

EFNB3 Reactivité: Humain, Souris Hôte: Synthetic BP, WB
N° du produit ABIN2185120
  • Antigène Tous les produits Ephrin B3 (EFNB3)
    Ephrin B3 (EFNB3)
    Protein Region
    C-Term
    Origine
    Humain, Souris
    Source
    • 2
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Séquence
    AGAGGAMCWR RRRAKPSESR HPGPGSFGRG GSLGLGGGGG MGPREAEPGE
    Attributs du produit
    This is a synthetic peptide designed for use in combination with anti-Efnb3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Conseil sur la manipulation
    Avoid repeat freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène
    Ephrin B3 (EFNB3)
    Synonymes
    efnb3-A Peptide, EphB3 Peptide, EFNB3 Peptide, efnb3 Peptide, id:ibd5049 Peptide, zgc:111938 Peptide, EFL-6 Peptide, ELF-3 Peptide, Elk-L3 Peptide, Epl8 Peptide, LERK-8 Peptide, NLERK-2 Peptide, ELK-L3 Peptide, RGD1565678 Peptide, EFL6 Peptide, EPLG8 Peptide, LERK8 Peptide, ephrin B3 Peptide, ephrin-B3 L homeolog Peptide, ephrin-B3b Peptide, ephrin-B3 Peptide, EFNB3 Peptide, efnb3.L Peptide, efnb3b Peptide, efnb3 Peptide, Efnb3 Peptide
    Sujet
    Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Efnb3 binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. It may play a pivotal role in forebrain function. It binds to, and induce the collapse of, commissural axons/growth cones in vitro. Efnb3 may play a role in constraining the orientation of longitudinally projecting axons.

    Alias Symbols: EFL-6, ELF-3, Elk-L3, Epl8, LERK-8, NLERK-2

    Protein Size: 340
    Poids moléculaire
    36 kDa
    ID gène
    13643
    NCBI Accession
    NM_007911, NP_031937
    UniProt
    O35393
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