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KH Domain Containing, RNA Binding, Signal Transduction Associated 2 (KHDRBS2) Peptide

KHDRBS2 Reactivité: Mammifères Hôte: Synthetic BP, WB, IHC
N° du produit ABIN937747
  • Antigène Tous les produits KHDRBS2
    KHDRBS2 (KH Domain Containing, RNA Binding, Signal Transduction Associated 2 (KHDRBS2))
    Type de proteíne
    Synthetic
    Origine
    Mammifères
    Source
    • 5
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    EEIEKFQGSD GKKEDEEKKY LDVISNKNIK LSERVLIPVK QYPKFNFVGK
    Attributs du produit
    A synthetic peptide for use as a blocking control in assays to test for specificity of KHDRBS2 antibody,
    Alternative Names: KHDRBS2 control peptide, KHDRBS2 antibody Blocking Peptide, Anti-KHDRBS2 Blocking Peptide, KH domain containing, RNA binding, signal transduction associated 2 Blocking Peptide, FLJ38664 Blocking Peptide, MGC26664 Blocking Peptide, SLM-1 Blocking Peptide, SLM1 Blocking Peptide, bA535F17.1 Blocking Peptide, KHDRBS2, KHDRBS-2, KHDRBS 2, KHDRBS-2 Blocking Peptide, KHDRBS 2 Blocking Peptide
  • Indications d'application
    Optimal conditions should be determined by the investigator
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
    Buffer
    PBS
    Conseil sur la manipulation
    Avoid repeated freeze/thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C long term.
  • Antigène
    KHDRBS2 (KH Domain Containing, RNA Binding, Signal Transduction Associated 2 (KHDRBS2))
    Synonymes
    slm1 Peptide, slm-1 Peptide, MGC145973 Peptide, ba535f17.1 Peptide, zgc:153588 Peptide, SLM-1 Peptide, SLM1 Peptide, bA535F17.1 Peptide, 6330586C16Rik Peptide, Slim1 Peptide, Slm1 Peptide, KH RNA binding domain containing, signal transduction associated 2 Peptide, KH domain containing, RNA binding, signal transduction associated 2 Peptide, KHDRBS2 Peptide, khdrbs2 Peptide, Khdrbs2 Peptide
    Sujet
    KHDRBS2 is a RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Its phosphorylation by FYN inhibits its ability to regulate splice site selection. KHDRBS2 induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. KHDRBS2 may function as an adapter protein for Src kinases during mitosis. KHDRBS2 binds both poly(A) and poly(U) homopolymers. Phosphorylation by PTK6 inhibits its RNA-binding ability.
    Poids moléculaire
    39 kDa
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