Forkhead Box O3 (FOXO3) Peptide
FOXO3
Reactivité: Humain
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits FOXO3
- FOXO3 (Forkhead Box O3 (FOXO3))
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-FOXO3 antibody (Catalog #: ARP38040_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- FOXO3 (Forkhead Box O3 (FOXO3))
- Sujet
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FOXO3A belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia.This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed.
Alias Symbols: AF6q21, DKFZp781A0677, FKHRL1, FKHRL1P2, FOXO2, FOXO3A, MGC12739, MGC31925
Protein Interaction Partner: CDKN1A,CDKN1B,CHUK,FOXG1,IKBKB,SIRT1,SMAD3,SMAD4,BCL2L11,AKT1,CHUK,EP300,ESR1,FOXG1,IKBKB,NR1H2,NR1H3,SGK1,SIRT1,SMAD2,SMAD3,SMAD4,YWHAG,YWHAZ,CTNNB1,SMAD3,SMAD4,TP53,USP7,YWHAZ
Protein Size: 673 - Poids moléculaire
- 71 kDa
- ID gène
- 2309
- NCBI Accession
- NM_001455, NP_001446
- UniProt
- O43524
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