×
Pour une meilleure utilisation, nous vous conseillons d’activer Javascript dans votre navigateur.
Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC) (Middle Region) Peptide
GCLC
Reactivité: Humain
Hôte: Synthetic
BP, IHC, WB
Détail du produit
(cache)
Antigène
Tous les produits GCLC
GCLC
(Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC))
Protein Region
Middle Region
Origine
Humain
Source
Toutes les hôtes sur GCLC Peptides
Synthetic
Application
Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
Séquence
RISKSRYDSI DSYLSKCGEK YNDIDLTIDK EIYEQLLQEG IDHLLAQHVA
Attributs du produit
This is a synthetic peptide designed for use in combination with anti-GCLC Antibody(ARP54577_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Purification
Purified
Alternatives
(show)
Information d'application
(cache)
Indications d'application
Each Investigator should determine their own optimal working dilution for specific applications.
Restrictions
For Research Use only
Stockage
(cache)
Format
Lyophilized
Reconstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Concentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Conseil sur la manipulation
Avoid repeated freeze-thaw cycles.
Stock
-20 °C
Stockage commentaire
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Détail du antigène
(cache)
Antigène
GCLC
(Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC))
Synonymes
GCLC Peptide, gclc Peptide, MGC146287 Peptide, 2259 Peptide, CG2259 Peptide, DmGCLC Peptide, DmGCS Peptide, DmGCSh Peptide, Dmel\\CG2259 Peptide, GCL Peptide, GCLc Peptide, GCSh Peptide, Gcs Peptide, Gcsh Peptide, DDBDRAFT_0186120 Peptide, DDBDRAFT_0231403 Peptide, DDB_0186120 Peptide, DDB_0231403 Peptide, GCS Peptide, GLCL Peptide, GLCLC Peptide, D9Wsu168e Peptide, GLCL-H Peptide, Ggcs-hs Peptide, Glclc Peptide, cb1049 Peptide, fe36e11 Peptide, wu:fe36e11 Peptide, glutamate-cysteine ligase catalytic subunit Peptide, glutamate-cysteine ligase, catalytic subunit Peptide, Glutamate-cysteine ligase catalytic subunit Peptide, gamma glutamylcysteine synthetase Peptide, glutamate-cysteine ligase, catalytic subunit L homeolog Peptide, glutamate-cysteine ligase, catalytic subunit S homeolog Peptide, gamma-glutamylcysteine synthetase Peptide, GCLC Peptide, gclc Peptide, Gclc Peptide, LbGCS Peptide, gcsA Peptide, gclc.L Peptide, gclc.S Peptide, GSH1 Peptide
Sujet
Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. GCLC is the catalytic subunit of 637 amino acids with a calculated molecular weight of 72.773 kDa. Deficiency of gamma-glutamylcysteine synthetase in human is associated with enzymopathic hemolytic anemia. Alias Symbols: GCL, GCS, GLCL, GLCLC Protein Size: 637
Poids moléculaire
73 kDa
ID gène
2729
NCBI Accession
NM_001498 , NP_001489
UniProt
P48506
Vus récemment
(cache)