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LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1) (Middle Region) Peptide

LIMS1 Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN979327
  • Antigène Tous les produits LIMS1
    LIMS1 (LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1))
    Protein Region
    Middle Region
    Origine
    Humain
    Source
    • 1
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Séquence
    HLCRPCHNRE KARGLGKYIC QKCHAIIDEQ PLIFKNDPYH PDHFNCANCG
    Attributs du produit
    This is a synthetic peptide designed for use in combination with anti-LIMS1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Indications d'application
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène
    LIMS1 (LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1))
    Synonymes
    PINCH Peptide, PINCH-1 Peptide, PINCH1 Peptide, Pinch1 Peptide, RGD1560732 Peptide, LIMS3 Peptide, LIMS3L Peptide, 2310016J22Rik Peptide, 4921524A02Rik Peptide, AI507642 Peptide, AU021743 Peptide, AW551584 Peptide, C430041B13Rik Peptide, Lims1l Peptide, LIM zinc finger domain containing 1 Peptide, LIM and senescent cell antigen-like domains 1 Peptide, LIMS1 Peptide, Lims1 Peptide
    Sujet
    The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene.

    Alias Symbols: PINCH, PINCH1

    Protein Size: 387
    Poids moléculaire
    44 kDa
    ID gène
    3987
    NCBI Accession
    NM_001193485, NP_001180414
    UniProt
    B7Z7R3
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