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Mucin 1 (MUC1) Peptide

MUC1 Reactivité: Humain Hôte: Synthetic BP, WB, IHC
N° du produit ABIN980374
  • Antigène Tous les produits MUC1
    MUC1 (Mucin 1 (MUC1))
    Origine
    Humain
    Source
    • 18
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Attributs du produit
    This is a synthetic peptide designed for use in combination with anti-MUC1 antibody (Catalog #: ARP41446_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Indications d'application
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène
    MUC1 (Mucin 1 (MUC1))
    Synonymes
    CA 15-3 Peptide, CD227 Peptide, EMA Peptide, H23AG Peptide, KL-6 Peptide, MAM6 Peptide, MCKD1 Peptide, MUC-1 Peptide, MUC-1/SEC Peptide, MUC-1/X Peptide, MUC1/ZD Peptide, PEM Peptide, PEMT Peptide, PUM Peptide, Muc-1 Peptide, mucin 1, cell surface associated Peptide, mucin 1, transmembrane Peptide, MUC1 Peptide, Muc1 Peptide
    Sujet
    MUC1 is a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas.

    Alias Symbols: CD227, EMA, PEM, PUM, mucin, KL-6, MAM6, PEMT, H23AG, MUC-1, MUC-1/X, MUC1/ZD, MUC-1/SEC

    Protein Interaction Partner: BAX,CDKN1A,TP53,CTNNB1,EGFR,SRC,ABL1,APC,CTNNB1,CTNNB1,CTNND1,CTNND1,EGFR,EGFR,ERBB2,ERBB2,ERBB3,ERBB3,ERBB4,ERBB4,GALNT1,GALNT1,GALNT10,GALNT10,GALNT12,GALNT2,GALNT2,GALNTL2,GALNTL2,GRB2,GRB2,GSK3B,GSK3B,JUP,JUP,LCK,LYN,OSGEP,OSGEP,PRKCD,PRKCD,SIGLEC1,SOS1,SOS1,SRC,SRC,ZAP70,APC,CTNNB1,CTNND1,Ctnnb1,EGFR,ERBB2,ERBB3,ERBB4,GALNT12,GALNT4,GRB2,GSK3B,JUP,LYN,PRKCD,SOS1,SRC

    Protein Size: 203
    Poids moléculaire
    22 kDa
    ID gène
    4582
    NCBI Accession
    NM_001044390, NP_001037855
    UniProt
    Q7Z552
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