Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) Peptide
AIFM1
Reactivité: Humain
Hôte: Synthetic
BP, WB, IHC
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- Antigène Tous les produits AIF (AIFM1)
- AIF (AIFM1) (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1))
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-PDCD8 antibody (Catalog #: AVARP00028_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- AIF (AIFM1) (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1))
- Synonymes
- AIF Peptide, CMTX4 Peptide, COWCK Peptide, COXPD6 Peptide, PDCD8 Peptide, CG7263 Peptide, DmAIF Peptide, Dmel\\CG7263 Peptide, GB16024 Peptide, DDBDRAFT_0187853 Peptide, DDBDRAFT_0191137 Peptide, DDB_0187853 Peptide, DDB_0191137 Peptide, aif Peptide, pdcd8 Peptide, AIFM1 Peptide, PCD8 Peptide, AIFsh2 Peptide, Hq Peptide, Pdcd8 Peptide, mAIF Peptide, Aif Peptide, zgc:91994 Peptide, apoptosis inducing factor mitochondria associated 1 Peptide, allograft inflammatory factor 1 Peptide, Apoptosis inducing factor Peptide, apoptosis-inducing factor 1, mitochondrial Peptide, apoptosis inducing factor Peptide, apoptosis inducing factor, mitochondria associated 1 Peptide, apoptosis-inducing factor, mitochondrion-associated, 1 Peptide, apoptosis-inducing factor, mitochondrion-associated 1 Peptide, AIFM1 Peptide, AIF1 Peptide, AIF Peptide, LOC412212 Peptide, aif Peptide, aifm1 Peptide, Aifm1 Peptide
- Sujet
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AIFM1 (PDCD8) is a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it effects chromosome condensation and fragmentation. In addition, AIFM1 induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9.This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it effects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Three alternative transcripts encoding different isoforms have been identified for this gene.This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it effects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Three alternative transcripts encoding different isoforms have been identified for this gene.
Alias Symbols: RP3-438D16.2, AIF, MGC111425, PDCD8, COXPD6
Protein Interaction Partner: C4orf14,CASP3,EIF3G,HSPA1A,HSPA1B,SETDB1,STC2,TSC22D4,WWC1,BRF2,C20orf24,HSPA1A,MLF2,MLH1,PELO,PMS2,PTP4A3,SETDB1,STC2,UBC,XIAP
Protein Size: 609 - Poids moléculaire
- 66 kDa
- ID gène
- 9131
- NCBI Accession
- NM_145812, NP_665811
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