6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1) (C-Term) Peptide
PFKFB1
Reactivité: Humain
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits PFKFB1
- PFKFB1 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1))
- Protein Region
- C-Term
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Séquence
- EEMTYEEIQE HYPEEFALRD QDKYRYRYPK GESYEDLVQR LEPVIMELER
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-PFKFB1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- PFKFB1 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1))
- Synonymes
- zgc:55328 Peptide, wu:fi11h10 Peptide, PFKFB1 Peptide, F6PK Peptide, HL2K Peptide, PFRX Peptide, Pfkfb01 Peptide, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 Peptide, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 S homeolog Peptide, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 Peptide, pfkfb1 Peptide, PFKFB1 Peptide, pfkfb1.S Peptide, LOC100475853 Peptide, Pfkfb1 Peptide
- Sujet
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This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis.
Alias Symbols: F6PK, HL2K, MGC116715, MGC116717, PFRX
Protein Size: 471 - Poids moléculaire
- 52 kDa
- ID gène
- 5207
- NCBI Accession
- NM_002625, NP_002616
- UniProt
- P16118
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