Prohibitin (PHB) Peptide
PHB
Reactivité: Humain
Hôte: Synthetic
BP, WB, IHC
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- Antigène Tous les produits Prohibitin (PHB)
- Prohibitin (PHB)
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-PHB antibody (Catalog #: ARP32807_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- Prohibitin (PHB)
- Synonymes
- phb1 Peptide, MGC75944 Peptide, PHB Peptide, Phb Peptide, ACYPI000080 Peptide, phb Peptide, PHB1 Peptide, Bap32 Peptide, sr:nyz128 Peptide, wu:fa18f07 Peptide, wu:fb09f05 Peptide, prohibitin1 Peptide, xphb1 Peptide, prohibitin Peptide, prohibitin-2 Peptide, prohibitin L homeolog Peptide, PHB Peptide, phb Peptide, LOC484431 Peptide, LOC5576054 Peptide, Phb Peptide, phb.L Peptide
- Sujet
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Prohibitin is from an evolutionarily conserved gene that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations in PHB have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region. The longer transcript is present at higher levels in proliferating tissues and cells, suggesting that this longer 3' untranslated region may function as a trans-acting regulatory RNA.
Alias Symbols: PHB1
Protein Interaction Partner: RAF1,SMARCA2,SMARCA4,ANXA2,E2F1,HDAC1,MAP3K10,NCOR1,RAF1,RB1,RBL1,RBL2,SIN3A,SMARCA2,SMARCA4,SUMO4,TP53,XPO1,ACTN1,ANXA2,BRE,E2F1,HDAC1,MYOD1,NCOR1,RAF1,RB1,RBL1,RBL2,SIN3A,SMARCA2,SMARCA4,TP53
Protein Size: 272 - Poids moléculaire
- 30 kDa
- ID gène
- 5245
- NCBI Accession
- NM_002634, NP_002625
- UniProt
- P35232
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