Protein Inhibitor of Activated STAT, 1 (PIAS1) (N-Term) Peptide
PIAS1
Reactivité: Humain
Hôte: Synthetic
BP, WB
-
- Antigène Tous les produits PIAS1
- PIAS1 (Protein Inhibitor of Activated STAT, 1 (PIAS1))
- Protein Region
- N-Term
- Origine
- Humain
-
Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-PIAS1 antibody (Catalog #: ARP39231_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
-
-
- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Antigène
- PIAS1 (Protein Inhibitor of Activated STAT, 1 (PIAS1))
- Synonymes
- 2900068C24Rik Peptide, Ddxbp1 Peptide, GBP Peptide, DDXBP1 Peptide, GU/RH-II Peptide, ZMIZ3 Peptide, ddxbp1 Peptide, gbp Peptide, pias Peptide, pias1-A Peptide, xPAIS1 Peptide, xPIAS1 Peptide, zmiz3 Peptide, protein inhibitor of activated STAT 1 Peptide, protein inhibitor of activated STAT, 1 Peptide, protein inhibitor of activated STAT, 1a Peptide, protein inhibitor of activated STAT 1 L homeolog Peptide, PIAS1 Peptide, Pias1 Peptide, pias1a Peptide, pias1.L Peptide
- Sujet
-
PIAS1 is a member of the mammalian PIAS [protein inhibitor of activated STAT-1 (signal transducer and activator of transcription-1)] family. This member contains a putative zinc-binding motif and a highly acidic region. It inhibits STAT1-mediated gene activation and the DNA binding activity, binds to Gu protein/RNA helicase II/DEAD box polypeptide 21, and interacts with androgen receptor (AR). It functions in testis as a nuclear receptor transcriptional coregulator and may have a role in AR initiation and maintenance of spermatogenesis.This gene encodes a member of the mammalian PIAS [protein inhibitor of activated STAT-1 (signal transducer and activator of transcription-1)] family. This member contains a putative zinc-binding motif and a highly acidic region. It inhibits STAT1-mediated gene activation and the DNA binding activity, binds to Gu protein/RNA helicase II/DEAD box polypeptide 21, and interacts with androgen receptor (AR). It functions in testis as a nuclear receptor transcriptional coregulator and may have a role in AR initiation and maintenance of spermatogenesis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: DDXBP1, GBP, GU/RH-II, MGC141878, MGC141879, ZMIZ3
Protein Interaction Partner: CEBPA,CEBPE,CASP8,CSRP2,ESR1,HTNVsSgp1,SUMO1,TP53,UBE2I,AR,AXIN1,CASP8,CEBPA,CEBPE,CHUK,CREBBP,CSRP2,DCLRE1A,DDX21,DNM1,DNMT3A,ELK3,ESR1,ESR2,GATA4,GRM8,JUN,MBD1,MDM2,MSX1,NIN,NR2F2,NR3C2,NR5A1,PGR,PIAS1,PIAS2,PIAS4,PRPF40A,PTK2,PTPN1,RELA,SATB2,SERBP1,SKIL,SMAD1,SMAD4,SMAD7,SNIP1,SP3,STAT1,SUFU,SUMO1,TBP,TP53,TP73,UBE2I,ZNF76,AKT1,AR,CSRP2,DNMT3A,MX1,SIAH1,SIAH2,SP3,STAB2,STAT1,SUMO1,SUMO2,TP53,UBE2I,ZMIZ2
Protein Size: 651 - Poids moléculaire
- 72 kDa
- ID gène
- 8554
- NCBI Accession
- NM_016166, NP_057250
- UniProt
- O75925
-
Vous êtes ici:
