PIAS3
(Protein Inhibitor of Activated STAT, 3 (PIAS3))
Protein Region
Middle Region
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
Attributs du produit
This is a synthetic peptide designed for use in combination with anti-PIAS3 antibody (Catalog #: ARP32763_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
PIAS3
Reactivité: Humain, Boeuf (Vache), Chien, Souris, Porc, Rat
Hôte: Synthetic
BP
Indications d'application
Each Investigator should determine their own optimal working dilution for specific applications.
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Concentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Conseil sur la manipulation
Avoid repeated freeze-thaw cycles.
Stock
-20 °C
Stockage commentaire
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Antigène
PIAS3
(Protein Inhibitor of Activated STAT, 3 (PIAS3))
Sujet
PIAS3 is a member of the protein inhibitor of activated STAT (PIAS) family. It also activates TGF-beta/SMAD transcriptional responses. This gene encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] family of transcriptional modulators. The protein functions as a SUMO (small ubiquitin-like modifier)-E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It directly binds to several transcription factors and either blocks or enhances their activity. Alternatively spliced transcript variants of this gene have been identified, but the full-length nature of some of these variants has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FLJ14651, ZMIZ5
Protein Interaction Partner: GEMIN4,ZFHX3,AR,ATF7IP,EP300,ESR1,ESR2,GEMIN4,GFI1,HABP4,HDAC1,HMGA2,MITF,NCOA2,NR3C2,OPN1LW,PGR,PRPF40A,RELA,SERBP1,SKIL,SMAD2,SMAD3,SMAD4,STAT3,TBP,ZFHX3,AR,CREBBP,EP300,GFI1,HMGA2,MITF,RELA,SIAH1,SIAH2,SMAD2,SMAD3,SMAD4,STAT3,TRIM32,UBC,ZMIZ1,ZMIZ2