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Pyruvate Kinase M2 (PKM2) (Middle Region) Peptide

PKM2 Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN981816
  • Antigène Tous les produits PKM2
    PKM2 (Pyruvate Kinase M2 (PKM2))
    Protein Region
    Middle Region
    Origine
    Humain
    Source
    • 3
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Séquence
    HLQLFEELRR LAPITSDPTE ATAVGAVEAS FKCCSGAIIV LTKSGRSAHQ
    Attributs du produit
    This is a synthetic peptide designed for use in combination with anti-PKM2 Antibody(ARP57789_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Indications d'application
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène
    PKM2 (Pyruvate Kinase M2 (PKM2))
    Synonymes
    CTHBP Peptide, OIP3 Peptide, PK3 Peptide, PKM2 Peptide, TCB Peptide, THBP1 Peptide, AA414905 Peptide, AL024370 Peptide, AL024424 Peptide, Pk-2 Peptide, Pk-3 Peptide, Pk3 Peptide, Pkm2 Peptide, PKM12 Peptide, PKM Peptide, pyruvate kinase M1/2 Peptide, pyruvate kinase, muscle Peptide, PKM Peptide, Pkm Peptide
    Sujet
    This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported.

    Alias Symbols: CTHBP, MGC3932, OIP3, PK3, PKM, TCB, THBP1, PKM2

    Protein Interaction Partner: RAF1,RAF1,ARAF,EXOSC5,HERC1,NDRG1,OLFM2,PKM2,RAF1,SHBG,SORBS2,ARAF,BANF1,EXOSC5,TRIM63

    Protein Size: 531
    Poids moléculaire
    58 kDa
    ID gène
    5315
    NCBI Accession
    NM_002654, NP_002645
    UniProt
    P11980
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