This is a synthetic peptide designed for use in combination with anti-WNT3 Antibody(ARP49956_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
WNT3
Reactivité: Humain, Souris
Hôte: Synthetic
BP, BI
Indications d'application
Each Investigator should determine their own optimal working dilution for specific applications.
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Concentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Conseil sur la manipulation
Avoid repeated freeze-thaw cycles.
Stock
-20 °C
Stockage commentaire
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Antigène
WNT3
(Wingless-Type MMTV Integration Site Family, Member 3 (WNT3))
Synonymes
INT4 Peptide, Ci-Wnt3 Peptide, WNT3 Peptide, int4 Peptide, Xwnt3 Peptide, wnt-3 Peptide, wnt3l Peptide, Xwnt-3 Peptide, wnt3 Peptide, Int-4 Peptide, Wnt-3 Peptide, wnt3-A Peptide, Wnt family member 3 Peptide, wingless-type MMTV integration site family, member 3 Peptide, proto-oncogene Wnt-3 Peptide, wingless-type MMTV integration site family member 3 Peptide, Wnt family member 3A Peptide, wingless-type MMTV integration site family member 3 L homeolog Peptide, WNT3 Peptide, Wnt3 Peptide, wnt3 Peptide, LOC468297 Peptide, WNT3A Peptide, wnt3.L Peptide
Sujet
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98 % amino acid identity to mouse Wnt3 protein, and 84 % to human WNT3A protein, another WNT gene product. The mouse studies show the requirement of Wnt3 in primary axis formation in the mouse. Studies of the gene expression suggest that this gene may play a key role in some cases of human breast, rectal, lung, and gastric cancer through activation of the WNT-beta-catenin-TCF signaling pathway. This gene is clustered with WNT15, another family member, in the chromosome 17q21 region.
Alias Symbols: INT4, MGC131950, MGC138321, MGC138323