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Human Polyclonal DAP Primary Antibody pour WB - ABIN1881249
Koren, Reem, Kimchi: DAP1, a novel substrate of mTOR, negatively regulates autophagy. dans Current biology : CB 2010
Show all 4 Pubmed References
DAP1 may have an important role in cell adhesion, migration and growth in the context of breast cancer and has significant associations with the apoptosis pathway.
DAP1 was found to be correlated with disease progression and long-term survival of the colorectal patients. DAP1 is also a pivotal regulator of the growth and apoptosis and cellular response to chemotherapy agents.
This study demonstrates an inverse association between DAP1 mRNA levels and tumour stage and clinical outcome in breast cancer
Mapping of the phosphorylation sites and analysis of phosphorylation mutants indicated that DAP1 is functionally silenced in growing cells through mTOR-dependent phosphorylations on Ser3 and Ser51
This gene encodes a basic, proline-rich, 15-kD protein. The protein acts as a positive mediator of programmed cell death that is induced by interferon-gamma.
, death-associated protein 1
, death-associated protein
, death associated protein 1
, bZ1F1.9.1 (death associated protein 1a)
, bZ1F1.9.2 (death associated protein 1a)
, death associated protein 1a