Profil protéine

This gene encodes a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease, Tay-Sachs disease, and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants encoding different isoforms.

Alternative names and synonyms associated with Prosaposin (PSAP)

• prosaposin (PSAP) anticorps
• prosaposin (Psap) anticorps
• prosaposin (psap) anticorps
• prosaposin (LOC100011417) anticorps
• prosaposin (LOC100304726) anticorps
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• prosaposin (LOC100526719) anticorps

• AI037048 anticorps
• cb759 anticorps
• GLBA anticorps
• SAP1 anticorps
• SGP-1 anticorps
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• SGP1A anticorps
• wu:fa14a06 anticorps
• wu:fb36e02 anticorps
• wu:fb58g07 anticorps

Protein level used designations for anti-Prosaposin (PSAP) Anticorps

proactivator polypeptide , sphingolipid activator protein-1 , snoRNA MBII-198 , sulfated glycoprotein 1 , prosaposin (sulfated glycoprotein, sphingolipid hydrolase activator) , prosaposin (variant Gaucher disease and variant metachromatic leukodystrophy) , prosaposin , proactivator polypeptide-like