Aperçu des produits pour anti-Apelin (APLN) Anticorps

Zebrafish Apelin (APLN) interaction partners

1. Apelin signaling regulates lymphatic development by promoting serine-threonine kinase Akt/protein kinase B (Montrer AKT1 Anticorps) activity in a VEGF-C (Montrer VEGFC Anticorps)/VEGF receptor (Montrer FLT1 Anticorps) 3-independent manner during zebrafish embryogenesis.

2. Apelin knockdown inhibits both hypoxia-induced endothelial cell proliferation in vitro and hypoxia-induced vessel regeneration in the caudal (Montrer CAD Anticorps) fin regeneration of zebrafish.

Mouse (Murine) Apelin (APLN) interaction partners

1. the expression of APLNR (APJ/AGTRL1 (Montrer APLNR Anticorps)), the only known receptor for apelin, is predominantly restricted to the endothelial cells.

2. apelin effects on dynamic mechanical characteristics of single ventricular cardiomyocytes

3. Study shows that apelin-13 ameliorates chronic normobaric hypoxia-induced anxiety-like behavior in mice. Anxiolytic effects of apelin-13 might be associated with an inhibition of NF-kappaB (Montrer NFKB1 Anticorps) and microglial activation in the hippocampus.

4. Results revealed that apelin-13 attenuated brain edema and reduced cellular death by suppressing apoptosis after intracerebral hemorrhage in mice.

5. Apelin-36-[L28C(30kDa (Montrer TAF10 Anticorps)-PEG (Montrer PAEP Anticorps))] provides a starting point for the development of diabetes therapeutics that are devoid of the blood pressure effects associated with canonical APJ (Montrer APLNR Anticorps) activation

6. miR (Montrer MLXIP Anticorps)-503 promotes cardiac fibrosis via miR (Montrer MLXIP Anticorps)-503-Apelin-13-TGF-beta (Montrer TGFB1 Anticorps)-CTGF (Montrer CTGF Anticorps)-collagen production pathway.

7. Apelin directly interferes with thrombin-mediated signaling pathways and platelet activation, secretion, and aggregation, but not with ADP and thromboxane A2-mediated pathways.

8. Apelin regulates inflammatory response, diminishes inflammatory remote organ damage and improves survival in an experimental model of burn sepsis, which is at least partly mediated by a phosphatidylinositol 3-kinase/protein kinase B (Montrer AKT1 Anticorps) dependent pathway.

9. apelin is a potential activator of inflammation factors through the PI3K/Akt (Montrer AKT1 Anticorps) and Erk (Montrer EPHB2 Anticorps) signaling pathway and is potential therapeutically relevant to inflammatory responses of microglia cells

10. we showed the effect of Apelin on RAW264.7 macrophage under normal and hypoxic condition, which could further influence the angiogenesis and inflammation process that promoted by macrophages.

Cow (Bovine) Apelin (APLN) interaction partners

1. APJ receptor (Montrer APLNR Anticorps) in granulosa cells and both apelin and the APJ receptor (Montrer APLNR Anticorps) in theca tissues are expressed in bovine ovary.

2. The data suggest that apelin/APJ (Montrer APLNR Anticorps) system is involved in the mechanism regulating angiogenesis during follicle maturation as well as during corpora lutea formation and function in the bovine ovary.

Human Apelin (APLN) interaction partners

1. In patients with acute obstructive coronary syndrome that had the V103V polymorphism of the APLN gene, they were at greater risk for coronary artery disease.

2. The aims of this study were to evaluate and correlate circulating chemerin (Montrer RARRES2 Anticorps), apelin, vaspin (Montrer SERPINA12 Anticorps), and omentin (Montrer ITLN1 Anticorps)-1 levels in obese type 2 diabetic Egyptian patients with coronary artery stenosis (CAS (Montrer CSE1L Anticorps)), and to assess their usefulness as noninvasive diagnostic biomarkers.

3. increase in VEGF (Montrer VEGFA Anticorps) and Apelin, and decrease in Annexin A5 (Montrer ANXA5 Anticorps) supports roles of hemo-dynamic alterations in fetoplacental circulation and structural alterations in uteroplacental bed occurring in preeclampsia.

4. these observations suggest apelin-APJ (Montrer APLNR Anticorps) signaling in hepatocytes functions to protect against lipid accumulation in liver through two signaling pathways, that is, via AMPK (Montrer PRKAA1 Anticorps) activation and PPARalpha (Montrer PPARA Anticorps) induction.

5. Studies suggest that apelin/APJ (Montrer APLNR Anticorps) system may be applied to the treatment of cancers by regulating apoptosis, which may play a vital role in anticancer therapy [review].

6. miR (Montrer MLXIP Anticorps)-497 contributes to oxLDL-induced lipid deposition in macrophages largely via targeting of apelin.

7. we have identified APLN as putative predictive bvz biomarker in CRC (Montrer CALR Anticorps) patients. High APLN levels predict a poor response to bvz therapy in CRC (Montrer CALR Anticorps).

8. Apelin-12 influences troponin I levels in the acute phase of STEMI, whereas during the non-acute phase, low apelin levels were associated with a high rate of MACE.

9. Apelin concentrations are associated with altered plaque stability mediator levels and atherosclerosis in patients with rheumatoid arthritis. These relations are partially dependent on population origin and systemic inflammatory status.

10. APLN and APLNR (Montrer APLNR Anticorps) are present in human ovarian cells and APLN increases IGF1 (Montrer IGF1 Anticorps)-induced steroidogenesis in granulosa cells through an increase in HSD3B (Montrer HSD3B1 Anticorps) protein expression and activation of the MAPK3 (Montrer MAPK3 Anticorps)/1 and Akt (Montrer AKT1 Anticorps) pathways. Therefore, APLN and APLNR (Montrer APLNR Anticorps) may play a role in human follicular development and the pathogenesis of PCOS.

Pig (Porcine) Apelin (APLN) interaction partners

1. Apelin and its receptor (APJ (Montrer APLNR Anticorps)) appear to regulate ovarian follicular functions such as steroidogenesis and proliferation via APJ (Montrer APLNR Anticorps) activation and different signaling pathways.

2. Pig Apelin mRNA was sequenced.