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Protein Phosphatase 1, Catalytic Subunit, alpha Isoform Produits

(Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA))
The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Catégories Protein Phosphatase 1, Catalytic Subunit, alpha Isoform en vedette

Protein Phosphatase 1, Catalytic Subunit, alpha Isoform Anticorps

High quality antibodies with extensive validation data.

Protein Phosphatase 1, Catalytic Subunit, alpha Isoform Kits ELISA

Reliable ELISA kits for a wide range of species.

Protein Phosphatase 1, Catalytic Subunit, alpha Isoform Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

Protein Phosphatase 1, Catalytic Subunit, alpha Isoform recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, ICC, IP
Validations
  • (7)
N° du produit ABIN7444715
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Rat
Application WB, ICC, IHC (p), IF
Validations
  • (1)
  • (5)
N° du produit ABIN2856071
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB
Validations
  • (5)
N° du produit ABIN6146053
Quantité 100 μL
Fiche technique Fiche technique

Protein Phosphatase 1, Catalytic Subunit, alpha Isoform recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6969734
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6206787
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Cow
Analytical Method
Validations
N° du produit ABIN1157567
Quantité 96 tests
Fiche technique Fiche technique

Protein Phosphatase 1, Catalytic Subunit, alpha Isoform recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7124661
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1315937
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1315939
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits Protein Phosphatase 1, Catalytic Subunit, alpha Isoform

Wu, Zhang, Peirats-Llobet, Belda-Palazon, Wang, Cui, Yu, Rodriguez, An: "Ubiquitin Ligases RGLG1 and RGLG5 Regulate Abscisic Acid Signaling by Controlling the Turnover of Phosphatase PP2CA." dans: The Plant cell, Vol. 28, Issue 9, pp. 2178-2196, (2016) (PubMed).

Wei, Ngo, Wu, Lee: "Phosphorylation of the Ndc80 complex protein, HEC1, by Nek2 kinase modulates chromosome alignment and signaling of the spindle assembly checkpoint." dans: Molecular biology of the cell, Vol. 22, Issue 19, pp. 3584-94, (2012) (PubMed).

Chen, Kesler, Paschal, Balk: "Androgen receptor phosphorylation and activity are regulated by an association with protein phosphatase 1." dans: The Journal of biological chemistry, Vol. 284, Issue 38, pp. 25576-84, (2009) (PubMed).

Perry, Yang, Soora, Salma, Marback, Naghibi, Ilyas, Chan, Gordon, McDermott: "Direct interaction between myocyte enhancer factor 2 (MEF2) and protein phosphatase 1alpha represses MEF2-dependent gene expression." dans: Molecular and cellular biology, Vol. 29, Issue 12, pp. 3355-66, (2009) (PubMed).

Gao, Zhou, Xie, Zhang, Rahmeh, Huang, Lee, Lee: "Protein phosphatase-1 is targeted to DNA polymerase delta via an interaction with the p68 subunit." dans: Biochemistry, Vol. 47, Issue 43, pp. 11367-76, (2008) (PubMed).

Moorhead, Trinkle-Mulcahy, Nimick, De Wever, Campbell, Gourlay, Lam, Lamond: "Displacement affinity chromatography of protein phosphatase one (PP1) complexes." dans: BMC biochemistry, Vol. 9, pp. 28, (2008) (PubMed).

Luo, Peterson, Garcia, Coombs, Kofahl, Heinrich, Shabanowitz, Hunt, Yost, Virshup: "Protein phosphatase 1 regulates assembly and function of the beta-catenin degradation complex." dans: The EMBO journal, Vol. 26, Issue 6, pp. 1511-21, (2007) (PubMed).

Eto, Kirkbride, Elliott, Lo, Brautigan: "Association of the tensin N-terminal protein-tyrosine phosphatase domain with the alpha isoform of protein phosphatase-1 in focal adhesions." dans: The Journal of biological chemistry, Vol. 282, Issue 24, pp. 17806-15, (2007) (PubMed).

Hsu, Huang, Seasholtz, Potter, Gollin: "Gene amplification and overexpression of protein phosphatase 1alpha in oral squamous cell carcinoma cell lines." dans: Oncogene, Vol. 25, Issue 40, pp. 5517-26, (2006) (PubMed).

Zhou, Boomer, Tan: "Protein phosphatase 4 is a positive regulator of hematopoietic progenitor kinase 1." dans: The Journal of biological chemistry, Vol. 279, Issue 47, pp. 49551-61, (2004) (PubMed).

Synonymes et noms alternatifs relatifs à Protein Phosphatase 1, Catalytic Subunit, alpha Isoform

protein phosphatase 1 catalytic subunit alpha (PPP1CA), protein phosphatase 1, catalytic subunit, alpha isoform (Ppp1ca), protein phosphatase 1 catalytic subunit alpha (Ppp1ca), protein phosphatase 1, catalytic subunit, alpha isozyme L homeolog (ppp1ca.L), protein phosphatase 1, catalytic subunit, alpha isozyme (ppp1ca), protein phosphatase 1, catalytic subunit, alpha isozyme a (ppp1caa), protein phosphatase 1, catalytic subunit, alpha isozyme b (ppp1cab), dism2, fb18b03, fd20h04, PP-1A, PP1A, PP1alpha, PPP1A, ppp1a, Ppp1c, Ppp1ca, wu:fb18b03, wu:fc04c08, wu:fc09b07, wu:fc30g11, wu:fd20h04, wu:fe05h08, wu:fl22a03, zgc:55744, zgc:76940, zgc:85729

Protein level used designations for Protein Phosphatase 1, Catalytic Subunit, alpha Isoform

  • protein phosphatase 1, catalytic subunit, alpha isoform
  • serine/threonine protein phosphatase PP1-alpha 1 catalytic subunit
  • serine/threonine-protein phosphatase PP1-alpha catalytic subunit
  • PP-1A
  • Protein phosphatase type 1 alpha, catalytic subunit
  • protein phosphatase-1d
  • ppp1ca
  • protein phosphatase 1, catalytic subunit, alpha
  • PP1 alpha
  • protein phosphatase 1 alpha
  • protein phosphatase 1, catalytic subunit, alpha-like
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