Profil protéine

Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family.

Alternative names and synonyms associated with Importin 5 (IPO5)

• importin 5 (IPO5) anticorps
• importin 5 (Ipo5) anticorps

• 1110011C18Rik anticorps
• 5730478E03Rik anticorps
• AA409333 anticorps
• C76941 anticorps
• IMB3 anticorps
• Afficher tous les alias de synonymes
• imp5 anticorps
• IPO5 anticorps
• Kpnb3 anticorps
• Pse1 anticorps
• Ranbp5 anticorps

Protein level used designations for anti-Importin 5 (IPO5) Anticorps

importin 5 , RAN binding protein 5 , Ran_GTP binding protein 5 , importin beta-3 subunit , importin subunit beta-3 , importin-5 , karyopherin (importin) beta 3 , karyopherin beta-3 , ran-binding protein 5 , imp5