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SNCA Protein (AA 1-139, partial) (GST tag)

SNCA Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant 90 % SDS, ELISA
N° du produit ABIN1046507
  • Antigène Voir toutes SNCA Protéines
    SNCA (Synuclein, alpha (SNCA))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 1-139, partial
    Origine
    • 26
    • 8
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Source
    • 27
    • 13
    • 3
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette SNCA protéine est marqué à la GST tag.
    Application
    SDS-PAGE (SDS), ELISA
    Séquence
    MDVFMKGLSK AKEGVVAAAE KTKQGVAEAA GKTKEGVLYV GSKTKEGVVH GVATVAEKTK EQVTNVGGAV VTGVTAVAQK TVEGAGSIAA ATGFVKKDQL GKNEEGAPQE GILEDMPVDP DNEAYEMPSE EGYQDYEPE
    Attributs du produit
    May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.
    Pureté
    90 %
    Top Product
    Discover our top product SNCA Protéine
  • Commentaires

    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS buffer, 20mM GSH
    Stock
    -20 °C
  • Uéda, Saitoh, Mori: "Tissue-dependent alternative splicing of mRNA for NACP, the precursor of non-A beta component of Alzheimer's disease amyloid." dans: Biochemical and biophysical research communications, Vol. 205, Issue 2, pp. 1366-72, (1995) (PubMed).

    Campion, Martin, Heilig, Charbonnier, Moreau, Flaman, Petit, Hannequin, Brice, Frebourg: "The NACP/synuclein gene: chromosomal assignment and screening for alterations in Alzheimer disease." dans: Genomics, Vol. 26, Issue 2, pp. 254-7, (1995) (PubMed).

    Uéda, Fukushima, Masliah, Xia, Iwai, Yoshimoto, Otero, Kondo, Ihara, Saitoh: "Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 90, Issue 23, pp. 11282-6, (1994) (PubMed).

  • Antigène
    SNCA (Synuclein, alpha (SNCA))
    Autre désignation
    alpha-Synuclein (SNCA Produits)
    Synonymes
    snca Protein, MGC64356 Protein, LOC619283 Protein, NACP Protein, alphaSYN Protein, PARK1 Protein, PARK4 Protein, PD1 Protein, synuclein alpha L homeolog Protein, alpha-synuclein Protein, synuclein alpha Protein, synuclein, alpha Protein, snca.L Protein, LOC619283 Protein, SNCA Protein, Snca Protein
    Sujet
    Synonyms: Non-A beta component of AD amyloid,Non-A4 component of amyloid precursor,NACP
    Poids moléculaire
    41.8 kD
    UniProt
    P37840
    Pathways
    Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity
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