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TNFRSF1A Protein (AA 31-210) (GST tag)

TNFRSF1A Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant 90 % ELISA
N° du produit ABIN1047844
  • Antigène Voir toutes TNFRSF1A Protéines
    TNFRSF1A (Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 31-210
    Origine
    • 29
    • 15
    • 5
    • 1
    • 1
    • 1
    Humain
    Source
    • 16
    • 15
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette TNFRSF1A protéine est marqué à la GST tag.
    Application
    ELISA
    Séquence
    VPHLGDREKR DSVCPQGKYI HPQNNSICCT KCHKGTYLYN DCPGPGQDTD CRECESGSFT ASENHLRHCL SCSKCRKEMG QVEISSCTVD RDTVCGCRKN QYRHYWSENL FQCFNCSLCL NGTVHLSCQE KQNTVCTCHA GFFLRENECV SCSNCKKSLE CTKLCLPQIE NVKGTEDSGT
    Attributs du produit
    Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.
    Pureté
    90 %
    Top Product
    Discover our top product TNFRSF1A Protéine
  • Commentaires

    The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Concentration
    0.2-2 mg/mL
    Buffer
    Tris-based buffer, 50 % glycerol
    Conseil sur la manipulation
    Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C for extended storage, conserve at -20 °C or -80 °C
  • Himmler, Maurer-Fogy, Krönke, Scheurich, Pfizenmaier, Lantz, Olsson, Hauptmann, Stratowa, Adolf: "Molecular cloning and expression of human and rat tumor necrosis factor receptor chain (p60) and its soluble derivative, tumor necrosis factor-binding protein." dans: DNA and cell biology, Vol. 9, Issue 10, pp. 705-15, (1991) (PubMed).

    Gray, Barrett, Chantry, Turner, Feldmann: "Cloning of human tumor necrosis factor (TNF) receptor cDNA and expression of recombinant soluble TNF-binding protein." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 87, Issue 19, pp. 7380-4, (1990) (PubMed).

    Schall, Lewis, Koller, Lee, Rice, Wong, Gatanaga, Granger, Lentz, Raab: "Molecular cloning and expression of a receptor for human tumor necrosis factor." dans: Cell, Vol. 61, Issue 2, pp. 361-70, (1990) (PubMed).

    Loetscher, Pan, Lahm, Gentz, Brockhaus, Tabuchi, Lesslauer: "Molecular cloning and expression of the human 55 kd tumor necrosis factor receptor." dans: Cell, Vol. 61, Issue 2, pp. 351-9, (1990) (PubMed).

    Nophar, Kemper, Brakebusch, Englemann, Zwang, Aderka, Holtmann, Wallach et al.: "Soluble forms of tumor necrosis factor receptors (TNF-Rs). The cDNA for the type I TNF-R, cloned using amino acid sequence data of its soluble form, encodes both the cell surface and a soluble form ..." dans: The EMBO journal, Vol. 9, Issue 10, pp. 3269-78, (1990) (PubMed).

  • Antigène
    TNFRSF1A (Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A))
    Autre désignation
    Tumor necrosis factor receptor superfamily member 1A protein (TNFRSF1A Produits)
    Synonymes
    CD120a Protein, FPF Protein, MS5 Protein, TBP1 Protein, TNF-R Protein, TNF-R-I Protein, TNF-R55 Protein, TNFAR Protein, TNFR1 Protein, TNFR1-d2 Protein, TNFR55 Protein, TNFR60 Protein, p55 Protein, p55-R Protein, p60 Protein, TNF-R1 Protein, TNF-alphaR1 Protein, TNFRI Protein, TNFRp55 Protein, TNFalpha-R1 Protein, Tnfr-2 Protein, Tnfr1 Protein, fpf Protein, tbp1 Protein, p55-r Protein, tnf-r Protein, tnfar Protein, tnfr1 Protein, cd120a Protein, tnfr55 Protein, tnfr60 Protein, xtnfr1 Protein, wu:fj65b10 Protein, zgc:85914 Protein, TNFR I Protein, TNFRSF1A Protein, TNFA Protein, cTNF Protein, TNF receptor superfamily member 1A Protein, tumor necrosis factor receptor superfamily, member 1a Protein, TNF receptor superfamily member 1A S homeolog Protein, tumor necrosis factor Protein, TNFRSF1A Protein, Tnfrsf1a Protein, tnfrsf1a.S Protein, tnfrsf1a Protein, TNF Protein
    Sujet
    Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.
    Poids moléculaire
    47.6 kD
    UniProt
    P19438
    Pathways
    Signalisation NF-kappaB, Apoptose, Caspase Cascade in Apoptosis, Hepatitis C, Ubiquitin Proteasome Pathway
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