BAG2 Protein (AA 1-211) (His tag)

N° du produit ABIN1096077

Détail du produit

Antigène: BAG2 (BCL2-Associated Athanogene 2 (BAG2))

Type de proteíne: Recombinant

Attributs du protein: AA 1-211

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette BAG2 protéine est marqué à la His tag.

Fonction: Recombinant Human Bcl-2-Associated Athanogene 1/BAG2 (N-6His)

Séquence: MGSSHHHHHH SSGLVPRGSH MAQAKINAKA NEGRFCRSSS MADRSSRLLE SLDQLELRVE ALREAATAVE QEKEILLEMI HSIQNSQDMR QISDGEREEL NLTANRLMGR TLTVEVSVET IRNPQQQESL KHATRIIDEV VNKFLDDLGN AKSHLMSLYS ACSSEVPHGP VDQKFQSIVI GCALEDQKKI KRRLETLLRN IENSDKAIKL LEHSKGAGSK TLQQNAESRF N

Attributs du produit: Recombinant Human BAG Family Molecular Chaperone Regulator 2/BAG2 is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Asn211) of Human BAG2 fused with a 6His tag at the N-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.

Conseil sur la manipulation: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Stock: 4 °C/-20 °C/-80 °C

Stockage commentaire: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 3 months

Détail du antigène

Antigène: BAG2 (BCL2-Associated Athanogene 2 (BAG2))

Autre désignation: BAG2 (BAG2 Produits)

Synonymes: bag2 Protein, MGC89300 Protein, BAG2 Protein, ATBAG2 Protein, BCL-2-associated athanogene 2 Protein, MTG10.13 Protein, MTG10_13 Protein, BAG-2 Protein, dJ417I1.2 Protein, zgc:64195 Protein, 2610042A13Rik Protein, BC016230 Protein, BCL2 associated athanogene 2 Protein, BCL-2-associated athanogene 2 Protein, BCL2-associated athanogene 2 Protein, Bcl2-associated athanogene 2 Protein, bag2 Protein, BAG2 Protein, Bag2 Protein

Sub Type: Fusionprotein

Sujet: BAG Family Molecular Chaperone Regulator 2 (BAG2) is a member of the Bag family whose members compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. BAG2 contains 1 BAG domain and is a important component of the HSC 70/CHIP chaperone-dependent ubiquitin ligase complex. In mammalian cells BAG1, BAG2, and BAG3 bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.
Alternative Names: BAG Family Molecular Chaperone Regulator 2, BAG-2, Bcl-2-Associated Athanogene 2, BAG2

Poids moléculaire: 25.9 kDa

UniProt: O95816