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CD200 Protein (CD200) (AA 21-232) (His tag)

CD200 Origine: Humain Hôte: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
N° du produit ABIN1096302
  • Antigène Voir toutes CD200 Protéines
    CD200
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 21-232
    Origine
    • 22
    • 8
    • 2
    • 1
    Humain
    Source
    • 16
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human Cells
    Purification/Conjugué
    Cette CD200 protéine est marqué à la His tag.
    Fonction
    Recombinant Human OX-2/MOX1/CD200 (C-6His)
    Séquence
    QVQVVTQDER EQLYTPASLK CSLQNAQEAL IVTWQKKKAV SPENMVTFSE NHGVVIQPAY KDKINITQLG LQNSTITFWN ITLEDEGCYM CLFNTFGFGK ISGTACLTVY VQPIVSLHYK FSEDHLNITC SATARPAPMV FWKVPRSGIE NSTVTLSHPN GTTSVTSILH IKDPKNQVGK EVICQVLHLG TVTDFKQTVN KGVDHHHHHH
    Attributs du produit
    Recombinant Human CD200 is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Val21-Gly232) of Human CD200 fused with a polyhistidine tag at the C-terminus.
    Pureté
    > 95 % as determined by reducing SDS-PAGE.
    Stérilité
    0.2 μm filtered
    niveau d'endotoxine
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product CD200 Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
    Conseil sur la manipulation
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Stock
    4 °C/-20 °C/-80 °C
    Stockage commentaire
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Date de péremption
    3 months
  • Antigène
    CD200
    Autre désignation
    cd200 (CD200 Produits)
    Synonymes
    MOX1 Protein, MOX2 Protein, MRC Protein, OX-2 Protein, CD200 Protein, Cspmo2 Protein, MRCOX2 Protein, Mox2 Protein, DKFZp459C0716 Protein, OX2 Protein, CD200 molecule Protein, Cd200 molecule Protein, CD200 antigen Protein, CD200 Protein, Cd200 Protein
    Sub Type
    Fusionprotein
    Sujet
    CD200 is a transmembrane immunoregulatory protein that belongs to the immunoglobulin superfamily. It contains one Ig like V type domain and one Ig like C2 type domain in its extracelluar domain. CD200 is widely but not ubiquitously expressed. Its receptor (CD200R) is restricted primarily to mast cells, basophils, macrophages, and dendritic cells, which suggests myeloid cell regulation as the major function of CD200. CD200 and CD200R associate via their respective N-terminal Ig-like domains. In myeloid cells, CD200R initiates inhibitory signals following receptor-ligand contact. In T cells, CD200 functions as a co-stimulatory molecule independent of the CD28 pathway. In addition, CD200 also plays an important role in prevention of graft rejection, autoimmune diseases and spontaneous abortion.
    Alternative Names: OX-2 Membrane Glycoprotein, CD200, MOX1, MOX2
    Poids moléculaire
    23.48 kDa
    UniProt
    P41217
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