CD36 Protein (CD36) (AA 27-432) (His tag)

N° du produit ABIN1096314

Détail du produit

Antigène: CD36

Type de proteíne: Recombinant

Attributs du protein: AA 27-432

Origine: Humain

Source: Human Cells

Purification/Conjugué: Cette CD36 protéine est marqué à la His tag.

Fonction: Recombinant Human Scavenger Receptor B2/SR-B2/LIMPII/CD36L2 (C-6His)

Séquence: RVFQKAVDQS IEKKIVLRNG TEAFDSWEKP PLPVYTQFYF FNVTNPEEIL RGETPRVEEV GPYTYRELRN KANIQFGDNG TTISAVSNKA YVFERDQSVG DPKIDLIRTL NIPVLTVIEW SQVHFLREII EAMLKAYQQK LFVTHTVDEL LWGYKDEILS LIHVFRPDIS PYFGLFYEKN GTNDGDYVFL TGEDSYLNFT KIVEWNGKTS LDWWITDKCN MINGTDGDSF HPLITKDEVL YVFPSDFCRS VYITFSDYES VQGLPAFRYK VPAEILANTS DNAGFCIPEG NCLGSGVLNV SICKNGAPII MSFPHFYQAD ERFVSAIEGM HPNQEDHETF VDINPLTGII LKAAKRFQIN IYVKKLDDFV ETGDIRTMVF PVMYLNESVH IDKETASRLK SMINTTLDHH HHHH

Attributs du produit: Recombinant Human Scavenger Receptor Class B Member 2/SCARB2 produced by transfected human cells is a secreted protein with sequence (Arg27-Thr432) of Human SCARB2 fused with a polyhistidine tag at the C-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

Conseil sur la manipulation: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Stock: 4 °C/-20 °C/-80 °C

Stockage commentaire: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 3 months

Détail du antigène

Antigène: CD36

Autre désignation: cd36 (CD36 Produits)

Synonymes: BDPLT10 Protein, CHDS7 Protein, FAT Protein, GP3B Protein, GP4 Protein, GPIV Protein, PASIV Protein, SCARB3 Protein, Fat Protein, Scarb3 Protein, GPIIIB Protein, PAS-4 Protein, zgc:92513 Protein, CD36 molecule Protein, CD36 molecule (thrombospondin receptor) Protein, CD36 Protein, Cd36 Protein, cd36 Protein

Sub Type: Fusionprotein

Sujet: Scavenger Receptor Class B Member 2 (SCARB2) is a type III multi-pass membrane glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes on all tissues and cell types so far examined. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is identified as a receptor for EV71 (human enterovirus species A, Enterovirus 71) and CVA16 (coxsackievirus A16) which are most frequently associated with hand, foot and mouth disease (HFMD). Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. In addition, SCARB2 also has been shown to bind thrombospondin-1, may contribute to the pro-adhesive changes of activated platelets during coagulation, and inflammation.
Alternative Names: Lysosome Membrane Protein 2, 85 kDa Lysosomal Membrane Sialoglycoprotein, LGP85, CD36 Antigen-Like 2, Lysosome Membrane Protein II, LIMP II, Scavenger Receptor Class B Member 2, CD36, SCARB2, CD36L2, LIMPII

Poids moléculaire: 47.59 kDa

UniProt: Q14108

Pathways: Signalisation TLR, Peptide Hormone Metabolism, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Hepatitis C, Toll-Like Receptors Cascades, Lipid Metabolism, S100 Proteins