CD55 Protein (AA 35-353) (His tag)

N° du produit ABIN1096332

Détail du produit

Antigène: CD55 (Complement Decay-Accelerating Factor (CD55))

Type de proteíne: Recombinant

Attributs du protein: AA 35-353

Origine: Humain

Source: Human Cells

Purification/Conjugué: Cette CD55 protéine est marqué à la His tag.

Fonction: Recombinant Human CD55/DAF (C-6His)

Séquence: DCGLPPDVPN AQPALEGRTS FPEDTVITYK CEESFVKIPG EKDSVICLKG SQWSDIEEFC NRSCEVPTRL NSASLKQPYI TQNYFPVGTV VEYECRPGYR REPSLSPKLT CLQNLKWSTA VEFCKKKSCP NPGEIRNGQI DVPGGILFGA TISFSCNTGY KLFGSTSSFC LISGSSVQWS DPLPECREIY CPAPPQIDNG IIQGERDHYG YRQSVTYACN KGFTMIGEHS IYCTVNNDEG EWSGPPPECR GKSLTSKVPP TVQKPTTVNV PTTEVSPTSQ KTTTKTTTPN AQATRSTPVS RTTKHFHETT PNKGSGTTSV DHHHHHH

Attributs du produit: Recombinant Human CD55 is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Asp35-Ser353) of Human CD55 fused with a polyhistidine tag at the C-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

Conseil sur la manipulation: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Stock: 4 °C/-20 °C/-80 °C

Stockage commentaire: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 3 months

Détail du antigène

Antigène: CD55 (Complement Decay-Accelerating Factor (CD55))

Autre désignation: cd55 (CD55 Produits)

Synonymes: CR Protein, CROM Protein, DAF Protein, TC Protein, Daf Protein, Daf-GPI Protein, Daf1 Protein, GPI-DAF Protein, CD55 molecule (Cromer blood group) Protein, CD55 molecule, decay accelerating factor for complement Protein, CD55 Protein, Cd55 Protein

Sub Type: Fusionprotein

Sujet: CD55 is a member of the RCA (regulators of complement activation) family. RCA proteins is characterized by the presence of four to 30 SCRs (short consensus repeats also called CCPs for control protein modules) in their plasmaexposed regions. CD55 containing four SCR modules is involved in the regulation of the complement cascade. CD55 is known to bind CD97 via the first SCR. It also binds physiologically generated C3 convertases with its second and third SCRs. Binding results in an accelerated “decay”, or dissociation of active C3 convertases, thus blocking the development of C’ attack complexes on nonforeign cells. It is known that viruses and bacteria also utilize multiple SCR sites for infection.
Alternative Names: Complement Decay-Accelerating factor, CD55, CR, DAF

Poids moléculaire: 36 kDa

UniProt: P08174

Pathways: Système du Complément, Regulation of Leukocyte Mediated Immunity