Recombinant Human C-Type Lectin Domain Family 3 Member B/CLEC3B produced by transfected human cells is a secreted protein with sequence (Glu22-Val202) of Human CLEC3B fused with a polyhistidine tag at the C-terminus.
Pureté
> 95 % as determined by reducing SDS-PAGE.
Stérilité
0.2 μm filtered
niveau d'endotoxine
Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
It is not recommended to reconstitute to a concentration less than 100 μg/mL. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Buffer
Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
Conseil sur la manipulation
Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
Stock
4 °C/-20 °C/-80 °C
Stockage commentaire
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Date de péremption
3 months
Antigène
CLEC3B
(C-Type Lectin Domain Family 3, Member B (CLEC3B))
Tna Protein, clec3b Protein, tetn Protein, TN Protein, TNA Protein, C-type lectin domain family 3, member B Protein, C-type lectin domain family 3 member B Protein, tetranectin Protein, C-type lectin domain family 3, member b Protein, Clec3b Protein, clec3b Protein, CLEC3B Protein, tetn Protein
Sub Type
Fusionprotein
Sujet
C-Type Lectin Domain Family 3 Member B (CLEC3B) is a serum and tissue protein and it contais a C-type lectin which binds to Ca++. CLEC3B is originally found in plasma, the concentrations approximately 10mg/l. It can bind to kringle 4 of plasminogen and enhance the activation of plaminogen to plasmin, catalyzed by tissue plasminogen activator in the presence of poly-D-lysine. In addition, CLEC3B may be involved in the packaging of molecules destined for exocytosis. Also, CLEC3B is best known as a prognostic marker in ovarian cancer. Alternative Names: Tetranectin, TN, C-Type Lectin Domain Family 3 Member B, Plasminogen Kringle 4-Binding Protein, CLEC3B, TNA