Kallikrein 4 Protein (AA 27-254) (His tag)

N° du produit ABIN1097011

Détail du produit

Antigène: Kallikrein 4 (KLK4) (Kallikrein-Related Peptidase 4 (KLK4))

Type de proteíne: Recombinant

Attributs du protein: AA 27-254

Origine: Humain

Source: Human Cells

Purification/Conjugué: Cette Kallikrein 4 protéine est marqué à la His tag.

Fonction: Recombinant Human Kallikrein 4/KLK4 (C-6His)

Séquence: SCSQIINGED CSPHSQPWQA ALVMENELFC SGVLVHPQWV LSAAHCFQNS YTIGLGLHSL EADQEPGSQM VEASLSVRHP EYNRPLLAND LMLIKLDESV SESDTIRSIS IASQCPTAGN SCLVSGWGLL ANGRMPTVLQ CVNVSVVSEE VCSKLYDPLY HPSMFCAGGG QDQKDSCNGD SGGPLICNGY LQGLVSFGKA PCGQVGVPGV YTNLCKFTEW IEKTVQASVD HHHHHH

Attributs du produit:

Recombinant Human Kallikrein 4/KLK4 (C-6His)

Pureté: > 95 % as determined by reducing SDS-PAGE.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.

Conseil sur la manipulation: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Stock: 4 °C/-20 °C/-80 °C

Stockage commentaire: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: Kallikrein 4 (KLK4) (Kallikrein-Related Peptidase 4 (KLK4))

Autre désignation: kallikrein-4 (KLK4 Produits)

Synonymes: ESMP1 Protein, KLK-L1 Protein, PSTS Protein, Prss17 Protein, AI2A1 Protein, ARM1 Protein, EMSP Protein, EMSP1 Protein, PRSS17 Protein, kallikrein Protein, Emsp1 Protein, kallikrein related-peptidase 4 (prostase, enamel matrix, prostate) Protein, kallikrein related peptidase 4 Protein, kallikrein-related peptidase 4 Protein, Klk4 Protein, KLK4 Protein

Sujet: Recombinant Human Kallikrein 4 is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (I31-S254) of Human KLK4 fused with a polyhistidine tag at the C-terminus.
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many Kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen members of the Kallikrein subfamily located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein.

Poids moléculaire: 25.44 kDa

UniProt: Q9Y5K2

Pathways: Système du Complément