PITRM1 Protein (AA 1-124) (His tag)

N° du produit ABIN1097179

Détail du produit

Antigène: PITRM1 (Pitrilysin Metallopeptidase 1 (PITRM1))

Type de proteíne: Recombinant

Attributs du protein: AA 1-124

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette PITRM1 protéine est marqué à la His tag.

Fonction: Recombinant Human MEK-Binding Protein 1/MP1/MAPKSP1 (N-6His)

Séquence: MGSSHHHHHH SSGLVPRGSH MADDLKRFLY KKLPSVEGLH AIVVSDRDGV PVIKVANDNA PEHALRPGFL STFALATDQG SKLGLSKNKS IICYYNTYQV VQFNRLPLVV SFIASSSANT GLIVSLEKEL APLFEELRQV VEVS

Attributs du produit: Recombinant Human Mitogen-Activated Protein Kinase Scaffold Protein 1/MAPKSP1 is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Val124) of Human LAMTOR3 fused with a 6His tag at the N-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 100 mM NaCl, 5 mM DTT, 30 % Glycerol, pH 8.0.

Agent conservateur: Dithiothreitol (DTT)

Précaution d'utilisation: This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Stock: -80 °C

Stockage commentaire: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Date de péremption: 6 months

Détail du antigène

Antigène: PITRM1 (Pitrilysin Metallopeptidase 1 (PITRM1))

Autre désignation: MP1 (PITRM1 Produits)

Synonymes: MP1 Protein, PreP Protein, 2310012C15Rik Protein, AA410010 Protein, MP-1 Protein, Ntup1 Protein, mKIAA1104 Protein, PITRM1 Protein, wu:fa03d09 Protein, zgc:55469 Protein, pitrilysin metallopeptidase 1 Protein, pitrilysin metallepetidase 1 Protein, pitrilysin metallopeptidase 1 L homeolog Protein, PITRM1 Protein, Pitrm1 Protein, pitrm1.L Protein, pitrm1 Protein

Sub Type: Fusionprotein

Sujet: Mitogen-Activated Protein Kinase Scaffold Protein 1 (MAPKSP1) was identified as an interacting protein that belongs to the LAMTOR3 family. MAPKSP1 restricted to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. MAPKSP1 interacts with MAP2K1/MEK1 and MAPK2 and enhances the activation of MAPK2, and thus is thought to function as an adaptor to enhance the efficiency of the MAP kinase cascade.
Alternative Names: Ragulator Complex Protein LAMTOR3, Late Endosomal/Lysosomal Adaptor and MAPK and MTOR Activator 3, MEK-Binding Partner 1, Mp1, Mitogen-Activated Protein Kinase Kinase 1-Interacting Protein 1, Mitogen-Activated Protein Kinase Scaffold Protein 1, LAMTOR3, M

Poids moléculaire: 15.78 kDa

UniProt: Q9UHA4

Pathways: Signalisation PI3K-Akt, SARS-CoV-2 Protein Interactome