OGG1 Protein (AA 1-345) (GST tag)

N° du produit ABIN1097188

Détail du produit

Antigène: OGG1 (8-Oxoguanine DNA Glycosylase (OGG1))

Type de proteíne: Recombinant

Attributs du protein: AA 1-345

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette OGG1 protéine est marqué à la GST tag.

Fonction: Recombinant Human N-Glycosylase/OGG1 (N-GST)

Séquence: MSPILGYWKI KGLVQPTRLL LEYLEEKYEE HLYERDEGDK WRNKKFELGL EFPNLPYYID GDVKLTQSMA IIRYIADKHN MLGGCPKERA EISMLEGAVL DIRYGVSRIA YSKDFETLKV DFLSKLPEML KMFEDRLCHK TYLNGDHVTH PDFMLYDALD VVLYMDPMCL DAFPKLVCFK KRIEAIPQID KYLKSSKYIA WPLQGWQATF GGGDHPPKSD LVPRGSMPAR ALLPRRMGHR TLASTPALWA SIPCPRSELR LDLVLPSGQS FRWREQSPAH WSGVLADQVW TLTQTEEQLH CTVYRGDKSQ ASRPTPDELE AVRKYFQLDV TLAQLYHHWG SVDSHFQEVA QKFQGVRLLR QDPIECLFSF ICSSNNNIAR ITGMVERLCQ AFGPRLIQLD DVTYHGFPSL QALAGPEVEA HLRKLGLGYR ARYVSASARA ILEEQGGLAW LQQLRESSYE EAHKALCILP GVGTKVADCI CLMALDKPQA VPVDVHMWHI AQRDYSWHPT TSQAKGPSPQ TNKELGNFFR SLWGPYAGWA QAVLFSADLR QSRHAQEPPA KRRKGSKGPE G

Attributs du produit: Recombinant Human N-Glycosylase/DNA Lyase is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Gly345) of Human DNA Lyase fused with a GST tag at the N-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 100 mM NaCl, 1 mM DTT, 1 mM EDTA, 50 % Glycerol, pH 7.8.

Agent conservateur: Dithiothreitol (DTT)

Précaution d'utilisation: This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Stock: -80 °C

Stockage commentaire: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Date de péremption: 6 months

Détail du antigène

Antigène: OGG1 (8-Oxoguanine DNA Glycosylase (OGG1))

Autre désignation: N-Glycosylase/DNA Lyase (OGG1 Produits)

Synonymes: OGG1 Protein, zgc:158858 Protein, 8-oxoguanine-DNA glycosylase 1 Protein, ARABIDOPSIS 8-OXOGUANINE-DNA GLYCOSYLASE 1 Protein, ATOGG1 Protein, F8K7.14 Protein, F8K7_14 Protein, 19.m02329 Protein, DDBDRAFT_0184479 Protein, DDBDRAFT_0233024 Protein, DDB_0184479 Protein, DDB_0233024 Protein, ogg1 Protein, Tb04.1H19.930 Protein, HMMH Protein, HOGG1 Protein, MUTM Protein, OGH1 Protein, Mmh Protein, 8-oxoguanine DNA glycosylase Protein, 8-oxoguanine DNA glycosylase L homeolog Protein, 8-oxoguanine-DNA glycosylase 1 Protein, 8-OXOGUANINE DNA GLYCOSYLASE Protein, putative 8-oxoguanine DNA glycosylase Protein, 8-oxoguanine DNA-glycosylase Protein, N-glycosylase/DNA lyase OGG1 Protein, 8-oxoguanine DNA-glycosylase 1 Protein, OGG1 Protein, ogg1.L Protein, ogg1 Protein, ECU08_0770 Protein, CA_C2707 Protein, BBOV_I004290 Protein, Smp_074010.1 Protein, LOC9329243 Protein, Tb927.4.2480 Protein, Ogg1 Protein

Sub Type: Fusionprotein

Sujet: Human N-Glycosylase/DNA Lyase is a DNA repair enzyme, which incises DNA at 8-oxoG residues, and excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damage DNA. DGG1 has a beta-lyase activity that nicks DNA 3’ to the lesion.
Alternative Names: N-Glycosylase/DNA Lyase, 8-Oxoguanine DNA Glycosylase, DNA-(Apurinic or Apyrimidinic Site) Lyase, AP Lyase, OGG1, MMH, MUTM, OGH1

Poids moléculaire: 65.07 kDa

UniProt: O15527

Pathways: Réparation de l'ADN