Oncomodulin Protein (OCM) (AA 2-109) (His tag)

N° du produit ABIN1097295

Détail du produit

Antigène: Oncomodulin (OCM)

Type de proteíne: Recombinant

Attributs du protein: AA 2-109

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette Oncomodulin protéine est marqué à la His tag.

Fonction: Recombinant Human Oncomodulin-1/OM (N-6His)

Séquence: MGSSHHHHHH SSGLVPRGSH MSITDVLSAD DIAAALQECR DPDTFEPQKF FQTSGLSKMS ANQVKDVFRF IDNDQSGYLD EEELKFFLQK FESGARELTE SETKSLMAAA DNDGDGKIGA EEFQEMVHS

Attributs du produit: Recombinant Human Oncomodulin-1/OM is produced by our E. coli expression system. The target protein is expressed with sequence (Ser2-Ser109) of Human OCM fused with a His tag at the N-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 50 mM Tris, 100 mM NaCl, pH 7.5.

Conseil sur la manipulation: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Stock: 4 °C/-20 °C/-80 °C

Stockage commentaire: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 3 months

Détail du antigène

Antigène: Oncomodulin (OCM)

Autre désignation: Parvalbumin-beta (OCM Produits)

Synonymes: OM Protein, Ocm Protein, oncmodulin Protein, OCM1 Protein, ONCM Protein, CBP-15 Protein, ocm1 Protein, oncm Protein, MGC189033 Protein, pvalb2 Protein, oncomodulin Protein, oncomodulin 2 Protein, Parvalbumin beta-like Protein, oncomodulin-1 Protein, oncomodulin L homeolog Protein, parvalbumin beta Protein, Ocm Protein, Ocm2 Protein, MGC53763 Protein, OCM Protein, LOC738473 Protein, ocm Protein, LOC100357024 Protein, ocm.L Protein, LOC100516001 Protein, LOC109097012 Protein, LOC102362774 Protein

Sub Type: Fusionprotein

Sujet: Oncomodulin-1 (OM) is a small, calcium-binding protein and a macrophage-derived growth factor, which can promote axon regeneration in retinal ganglion cells. Oncomodulin-1 is constitutively secreted by activated macrophages in the vitreous and retina in response to inflammatory conditions that promote optic nerve regeneration. Oncomodulin-1 binds RGCs with high affinity in vitro, but only when cAMP is pharmacologically elevated or if the membrane is permeabilized allowing Oncomodulin-1 access to the cytosolic compartment. Oncomodulin-1 is a member of the superfamily of calmodulin proteins and is a high-affinity calcium ion-binding protein and contains 2 EF-hand domains. OM is found in early embryonic cells in the placenta and also in tumors. It has some calmodulin-like activity with respect to enzyme activation and growth regulation.
Alternative Names: Oncomodulin-1, OM, Parvalbumin Beta, OCM, OCM1, OCMN

Poids moléculaire: 14.3 kDa

UniProt: P0CE72